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流感病毒、呼吸道合胞病毒和仙台病毒对人淋巴细胞和巨噬细胞的不同影响。

Different effects of influenza virus, respiratory syncytial virus, and Sendai virus on human lymphocytes and macrophages.

作者信息

Roberts N J

出版信息

Infect Immun. 1982 Mar;35(3):1142-6. doi: 10.1128/iai.35.3.1142-1146.1982.

Abstract

Influenza virus, respiratory syncytial virus, and Sendai virus depress human cell-mediated immune responses, such as mitogen-induced lymphocyte transformation, but differ in their ability to induce other immune defense mechanisms, such as interferon production. Exposure to the different viruses resulted in depressed transformation responses to the mitogen phytohemagglutinin by affecting the function of lymphocytes, or macrophages, or both cell types.

摘要

流感病毒、呼吸道合胞病毒和仙台病毒会抑制人类细胞介导的免疫反应,如丝裂原诱导的淋巴细胞转化,但它们在诱导其他免疫防御机制(如干扰素产生)的能力上有所不同。接触不同病毒会通过影响淋巴细胞或巨噬细胞或这两种细胞类型的功能,导致对丝裂原植物血凝素的转化反应受到抑制。

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