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人淋巴细胞制剂对不同病毒的复制或灭活作用。

Replication or inactivation of different viruses by human lymphocyte preparations.

作者信息

Denman A M, Rager-Zisman B, Merigan T C, Tyrrell D A

出版信息

Infect Immun. 1974 Feb;9(2):373-6. doi: 10.1128/iai.9.2.373-376.1974.

Abstract

Cultures of phytohemagglutinin-stimulated, unstimulated, and frozen and thawed mononuclear (as controls) cells from normal human donors were infected with different viruses. A variable pattern of virus infectivity was noted, and influenza and Coxsackie virus were rapidly inactivated even by stimulated lymphocytes. Direct inactivation by lymphocytes may be one form of host defense in infection by some viruses.

摘要

来自正常人类供体的经植物血凝素刺激、未经刺激以及冻融单核细胞(作为对照)的培养物被不同病毒感染。观察到病毒感染性的可变模式,并且流感病毒和柯萨奇病毒即使被刺激的淋巴细胞也能迅速灭活。淋巴细胞的直接灭活可能是宿主对某些病毒感染的一种防御形式。

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