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抗独特型抗体引发普劳斯尼茨-屈斯特纳反应。

Elicitation of the prausnitz-kustner reaction by antiidiotypic antibodies.

作者信息

Geha R S

出版信息

J Clin Invest. 1982 Apr;69(4):735-41. doi: 10.1172/jci110511.

DOI:10.1172/jci110511
PMID:6176594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC370126/
Abstract

Rabbit antiidiotypic IgG directed against IgG F(ab')2 anti-tetanus toxoid (TT) antibodies ("idiotype") elicited a Prausnitz-Kustner reaction in normal skin sites sensitized 48 h earlier with the serum of the idiotype donor that contained IgE anti-TT antibodies. The serum moiety that caused the sensitization was heat sensitive (56 degrees C, 1 h), and was specifically removed by passage over immunosorbents containing rabbit antihuman IgE or TT antigen. The data obtained indicate that human IgG and IgE antibodies share idiotypic determinants and raise the possibility that idiotypic interactions may play a role in the regulation of the IgE antibody response in man.

摘要

针对抗破伤风类毒素（TT）抗体的IgG F(ab')2（“独特型”）的兔抗独特型IgG，在48小时前用含有抗TT IgE抗体的独特型供体血清致敏的正常皮肤部位引发了普劳斯尼茨 - 屈斯特纳反应。引起致敏的血清部分对热敏感（56℃，1小时），并且通过与含有兔抗人IgE或TT抗原的免疫吸附剂孵育可特异性去除。所获得的数据表明，人IgG和IgE抗体共享独特型决定簇，并增加了独特型相互作用可能在人类IgE抗体反应调节中起作用的可能性。

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本文引用的文献

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Suppression of the benzylpenicilloyl- (BPO) specific IgE formation with isologous anti-idiotypic antibodies in BALB/c mice.在BALB/c小鼠中用同源抗独特型抗体抑制苄青霉素酰基（BPO）特异性IgE的形成。
J Immunol. 1980 Jul;125(1):24-30.
2
In vitro studies of IgE synthesis by human blood mononuclear cells.人血单核细胞 IgE 合成的体外研究。
Fed Proc. 1981 Jun;40(8):2167-70.
3
A clonal analysis of the IgE response and its implications with regard to isotope commitment.IgE 应答的克隆分析及其与同种型定向的关系
J Exp Med. 1981 Apr 1;153(4):783-92. doi: 10.1084/jem.153.4.783.
4
Dynamics of human circulating antigen reactive cells following secondary immunization with tetanus toxoid.破伤风类毒素二次免疫后人体循环抗原反应性细胞的动态变化。
Clin Immunol Immunopathol. 1981 May;19(2):196-205. doi: 10.1016/0090-1229(81)90063-5.
5
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J Immunol. 1980 Nov;125(5):2154-60.
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