Lampman R M, Santinga J T, Bassett D R, Mercer N, Block W O, Flora J D, Foss M L, Thorland W G
Circulation. 1978 Jan;57(1):172-80. doi: 10.1161/01.cir.57.1.172.
The effect of high intensity physical training (HIPT), conducted in an unsupervised (group A) or supervised (group B) setting, was studied in 23 middle-aged men with Type IV hyperlipoproteinemia (HLP). Following 10 weeks of HIPT intervention, significant metabolic changes were observed such as reductions in both fasting triglyceride and insulin levels, but no changes in fasting serum cholesterol or glucagon levels were found. Other favorable results noted included a significant improvement in physical fitness, as measured by increases in aerobic power, and a decrease in body fatness with only minimal weight losses. There were no significant differences in the results when groups A and B were compared. It was concluded that HIPT is an effective means of lowering fasting triglyceride and insulin levels in Type IV HLP individuals. In addition, such physical training programs can be conducted in either an unsupervised or supervised setting, provided the subjects are highly motivated.
对23名患有IV型高脂蛋白血症（HLP）的中年男性进行了研究，比较在无监督（A组）或有监督（B组）环境下进行高强度体育训练（HIPT）的效果。经过10周的HIPT干预后，观察到显著的代谢变化，如空腹甘油三酯和胰岛素水平均降低，但空腹血清胆固醇或胰高血糖素水平未发现变化。其他观察到的有利结果包括，通过有氧能力增加衡量的身体素质显著改善，以及体脂减少且体重仅有少量减轻。比较A组和B组的结果时未发现显著差异。得出的结论是，HIPT是降低IV型HLP个体空腹甘油三酯和胰岛素水平的有效方法。此外，只要受试者积极性高，此类体育训练项目可以在无监督或有监督的环境下进行。
