DR4 β链与疾病严重程度/狼疮性肾炎相关的分子多态性
Dw/LD-related molecular polymorphism of DR4 beta-chains.
作者信息
Groner J P, Watson A J, Bach F H
出版信息
J Exp Med. 1983 May 1;157(5):1687-91. doi: 10.1084/jem.157.5.1687.
Abstract
The results of this study demonstrate the existence of molecular heterogeneity (polymorphism) within DR beta-chains isolated from a single serologically defined DR phenotype, DR4. The data are consistent with the possibility that this polymorphism is related to the Dw/LD phenotype as defined with the cellular reagents, homozygous typing cells.
摘要
本研究结果表明，从单一血清学定义的DR表型DR4分离出的DRβ链中存在分子异质性（多态性）。这些数据与这种多态性可能与用细胞试剂纯合分型细胞定义的Dw/LD表型相关的可能性一致。
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本文引用的文献
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Cell membrane polymorphisms coded for in the HLA-D/DR region. I. Relation between D and DR.
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