Townsend A R, Skehel J J, Taylor P M, Palese P
Virology. 1984 Mar;133(2):456-9. doi: 10.1016/0042-6822(84)90413-6.
Cytotoxic T-cell clones raised against X-31 (H3N2) influenza virus in C57BL/6 mice can be directed against an influenza A virus subtype specific determinant (1). A representative T-cell clone (A3.1) has been used in combination with a set of genetically typed recombinant viruses, to show that the A/PR/8/34 nucleoprotein can be responsible for cytotoxic T-lymphocyte recognition of infected target cells.
在C57BL/6小鼠中产生的针对X-31（H3N2）流感病毒的细胞毒性T细胞克隆可针对甲型流感病毒亚型特异性决定簇（1）。一个具有代表性的T细胞克隆（A3.1）已与一组基因分型的重组病毒联合使用，以表明A/PR/8/34核蛋白可能是细胞毒性T淋巴细胞识别感染靶细胞的原因。
