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采用高效液相色谱-电化学检测法测定脑核中单胺类物质:年轻大鼠与中年大鼠的比较

Determination of monoamines in brain nuclei by high performance liquid chromatography with electrochemical detection: young vs. middle aged rats.

作者信息

Renner K J, Luine V N

出版信息

Life Sci. 1984 May 28;34(22):2193-9. doi: 10.1016/0024-3205(84)90320-5.

Abstract

A previously described high performance liquid chromatographic method for simultaneously measuring norepinephrine, dopamine, serotonin and 5-hydroxyindole acetic acid has been modified to permit analysis of the monoamines in microdissected brain nuclei from a single rat. Results of measurements in 12 nuclei of young and middle aged male rats are presented.

摘要

一种先前描述的用于同时测量去甲肾上腺素、多巴胺、5-羟色胺和5-羟吲哚乙酸的高效液相色谱法已被改进,以允许对来自单只大鼠的显微切割脑核中的单胺进行分析。本文给出了对年轻和中年雄性大鼠12个脑核的测量结果。

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