• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在小鼠生物变种外膜蛋白上检测到沙眼衣原体种特异性表位。

Chlamydia trachomatis species-specific epitope detected on mouse biovar outer membrane protein.

作者信息

Stephens R S, Kuo C C

出版信息

Infect Immun. 1984 Sep;45(3):790-1. doi: 10.1128/iai.45.3.790-791.1984.

DOI:10.1128/iai.45.3.790-791.1984
PMID:6205997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC263370/
Abstract

A common antigenic determinant on the chlamydial major outer membrane protein was detected on each of the three Chlamydia trachomatis biovars (trachoma, lymphogranuloma venereum, and mouse). This determinant was prominently displayed on the surface of chlamydial strains from both the trachoma and lymphogranuloma venereum biovars. However, detection of this determinant on a mouse biovar strain required denaturation by sodium dodecyl sulfate or periodate oxidation. This determinant provides a definable taxonomic link between the three biovars of C. trachomatis.

摘要

在沙眼衣原体的三种生物变种(沙眼、性病性淋巴肉芽肿和鼠生物变种)的每一种中都检测到了衣原体主要外膜蛋白上的一种共同抗原决定簇。这种决定簇在沙眼和性病性淋巴肉芽肿生物变种的衣原体菌株表面显著呈现。然而,在鼠生物变种菌株上检测到这种决定簇需要通过十二烷基硫酸钠变性或高碘酸盐氧化。这种决定簇为沙眼衣原体的三种生物变种之间提供了一个可明确界定的分类学联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97db/263370/8c111cc75607/iai00126-0263-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97db/263370/8c111cc75607/iai00126-0263-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97db/263370/8c111cc75607/iai00126-0263-a.jpg

相似文献

1
Chlamydia trachomatis species-specific epitope detected on mouse biovar outer membrane protein.在小鼠生物变种外膜蛋白上检测到沙眼衣原体种特异性表位。
Infect Immun. 1984 Sep;45(3):790-1. doi: 10.1128/iai.45.3.790-791.1984.
2
Immunochemical analysis of antigenic determinants of Chlamydia trachomatis by monoclonal antibodies.
J Gen Microbiol. 1983 Aug;129(8):2343-50. doi: 10.1099/00221287-129-8-2343.
3
Functional and structural mapping of Chlamydia trachomatis species-specific major outer membrane protein epitopes by use of neutralizing monoclonal antibodies.利用中和性单克隆抗体对沙眼衣原体种特异性主要外膜蛋白表位进行功能和结构图谱分析。
Infect Immun. 1991 Nov;59(11):4147-53. doi: 10.1128/iai.59.11.4147-4153.1991.
4
The low-molecular-mass, cysteine-rich outer membrane protein of Chlamydia trachomatis possesses both biovar- and species-specific epitopes.沙眼衣原体的低分子量、富含半胱氨酸的外膜蛋白具有生物变种特异性和种特异性表位。
Infect Immun. 1987 Nov;55(11):2570-3. doi: 10.1128/iai.55.11.2570-2573.1987.
5
Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis.保护性单克隆抗体识别位于沙眼衣原体主要外膜蛋白上的表位。
J Immunol. 1987 Jan 15;138(2):575-81.
6
Differences in outer membrane proteins of the lymphogranuloma venereum and trachoma biovars of Chlamydia trachomatis.沙眼衣原体性病淋巴肉芽肿生物变种与沙眼生物变种外膜蛋白的差异。
Infect Immun. 1985 Nov;50(2):488-94. doi: 10.1128/iai.50.2.488-494.1985.
7
Detection of surface-exposed epitopes on Chlamydia trachomatis by immune electron microscopy.
J Gen Microbiol. 1989 Jan;135(1):85-94. doi: 10.1099/00221287-135-1-85.
8
Neutralization of Chlamydia trachomatis infectivity with antibodies to the major outer membrane protein.用针对主要外膜蛋白的抗体中和沙眼衣原体的感染性。
Infect Immun. 1982 Nov;38(2):745-54. doi: 10.1128/iai.38.2.745-754.1982.
9
Analysis of the human serological response to proteins of Chlamydia trachomatis.对沙眼衣原体蛋白质的人体血清学反应分析。
Infect Immun. 1982 Dec;38(3):1181-9. doi: 10.1128/iai.38.3.1181-1189.1982.
10
Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge.针对沙眼衣原体小鼠肺炎生物变种主要外膜蛋白的单克隆免疫球蛋白A抗体可保护小鼠免受衣原体生殖道感染的挑战。
Vaccine. 1997 Apr;15(5):575-82. doi: 10.1016/s0264-410x(97)00206-5.

引用本文的文献

1
The growing repertoire of genetic tools for dissecting chlamydial pathogenesis.用于解析衣原体发病机制的遗传工具不断增多。
Pathog Dis. 2021 May 11;79(5). doi: 10.1093/femspd/ftab025.
2
Antigenic analysis of the major outer membrane protein of Chlamydia trachomatis with murine monoclonal antibodies.
Infect Immun. 1986 Sep;53(3):530-3. doi: 10.1128/iai.53.3.530-533.1986.

本文引用的文献

1
Deoxyribonucleic Acid Heterogeneity Between Human and Murine Strains of Chlamydia trachomatis.沙眼衣原体人源和鼠源株间的脱氧核糖核酸异质性。
Infect Immun. 1970 Jul;2(1):24-8. doi: 10.1128/iai.2.1.24-28.1970.
2
Monoclonal antibodies to Chlamydia trachomatis: antibody specificities and antigen characterization.抗沙眼衣原体单克隆抗体:抗体特异性及抗原特性
J Immunol. 1982 Mar;128(3):1083-9.
3
A rapid method for determining whether monoclonal antibodies react with the same or different antigens on the cell surface.
J Immunol Methods. 1980;39(4):377-85. doi: 10.1016/0022-1759(80)90238-0.
4
Culture-independent diagnosis of Chlamydia trachomatis using monoclonal antibodies.使用单克隆抗体对沙眼衣原体进行非培养诊断。
N Engl J Med. 1984 May 3;310(18):1146-50. doi: 10.1056/NEJM198405033101803.
5
Specific and common antigens of Trichomonas vaginalis detected by monoclonal antibodies.用单克隆抗体检测阴道毛滴虫的特异性和共同抗原。
Infect Immun. 1984 Jan;43(1):270-5. doi: 10.1128/iai.43.1.270-275.1984.
6
Sensitivity of immunofluorescence with monoclonal antibodies for detection of Chlamydia trachomatis inclusions in cell culture.用单克隆抗体进行免疫荧光检测细胞培养中沙眼衣原体包涵体的敏感性。
J Clin Microbiol. 1982 Jul;16(1):4-7. doi: 10.1128/jcm.16.1.4-7.1982.
7
Antigenic analysis of Chlamydiae by two-dimensional immunoelectrophoresis. II. A trachoma-LGV-specific antigen.用二维免疫电泳法对衣原体进行抗原分析。II. 一种沙眼-淋巴肉芽肿性尿道炎特异性抗原。
J Immunol. 1975 Oct;115(4):969-75.