Devi P U, Saharan B R
Experientia. 1978 Jan 15;34(1):91-2. doi: 10.1007/BF01921922.
The radiosensitivity of primary spermatocytes in pachytene stage was estimated by counting the number of spermatids in the testes of control and MPG-treated mouse after exposure to 500, 1000 and 1500 R of Co60 gamma-rays. For this purpose, control and MPG-treated mice were killed 5 days after irradiation and countings of spermatids was made in stages I and II of the tubules. It has been observed that, although there was a death of primary spermatocytes in irradiated MPG-protected groups, quantitatively significant protection was afforded by this drug at all the 3 dose-levels studied.
通过计数对照小鼠和经MPG处理的小鼠在接受500、1000和1500伦琴的钴60γ射线照射后睾丸中精子细胞的数量，来估计处于粗线期的初级精母细胞的放射敏感性。为此，在照射后5天处死对照小鼠和经MPG处理的小鼠，并对曲细精管的I期和II期的精子细胞进行计数。据观察，虽然在接受照射的MPG保护组中存在初级精母细胞死亡的情况，但在所有研究的3个剂量水平下，该药物都提供了具有定量意义的保护作用。
