Butler N R, Golding J, Haslum M, Stewart-Brown S
J R Soc Med. 1982 Oct;75(10):781-4. doi: 10.1177/014107688207501007.
The progress is described of the longtudinal cohort study based on all children born in England, Scotland and Wales in one week of April 1970. The children and their mothers have been surveyed at birth, at five, and recently, at ten. Analyses of the data presented include the finding of improved intellectual outcome in children who had been immunized against pertussis, compared with poor intellectual outcome in children who had had hospital admissions for the disease itself. Preliminary data collected at 10 show that routine hearing and vision testing during the child's school life fell short of recommended standards. The major aim of the 10-year-old contact, however, is to establish details of the national prevalence and pathogenesis of disability. The identification of disability uses a life skills questionnaire, medical history and examination.
本文描述了一项基于1970年4月某一周在英格兰、苏格兰和威尔士出生的所有儿童的纵向队列研究进展。这些儿童及其母亲在出生时、5岁时以及最近在10岁时均接受了调查。所呈现数据的分析包括以下发现：与因百日咳本身住院的儿童智力发育不良相比，接种过百日咳疫苗的儿童智力发育结果有所改善。10岁时收集的初步数据显示，儿童在校期间的常规听力和视力测试未达到推荐标准。然而，对10岁儿童进行随访的主要目的是确定全国残疾患病率和发病机制的详细情况。残疾的识别采用生活技能问卷、病史和检查。
