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输血的抗核心抗体筛查。

Anticore antibody screening of transfused blood.

作者信息

Lander J J, Gitnick G L, Gelb L H, Aach R D

出版信息

Vox Sang. 1978;34(2):77-80. doi: 10.1111/j.1423-0410.1978.tb03726.x.

DOI:10.1111/j.1423-0410.1978.tb03726.x
PMID:622820
Abstract

Aliquots of 130 HB8Ag negative units of blood which were administered to 26 recipients were tested under code for anti-HBc by a solid phase radioimmunoassay technqiue. 14 of the 26 recipients developed posttransfusion hepatitis (PTH), including 6 cases of hepatitis B. Anti-HBc was detected in 7 or 5.3% of 130 donor units. Of the 14 patients acquiring PTH, 6 received a unit of anti-HBc-positive blood. Type B hepatitis occurred in 4 of the 7 anti-HBc recipients, and non-type B hepatitis in 2. Only 1 of 12 recipients who failed to develop PTH had received a unit containing anti-HBc.

摘要

对输注给26名受血者的130个HB8Ag阴性血液样本采用固相放射免疫分析技术进行抗乙肝核心抗体(anti-HBc)的编码检测。26名受血者中有14人发生了输血后肝炎(PTH),其中包括6例乙型肝炎。在130个供血者样本中有7个(占5.3%)检测到anti-HBc。在发生PTH的14名患者中,有6人接受了anti-HBc阳性血液。7名anti-HBc受血者中有4人发生了乙型肝炎,2人发生了非乙型肝炎。在未发生PTH的12名受血者中,只有1人接受了含有anti-HBc的血液样本。

相似文献

1
Anticore antibody screening of transfused blood.输血的抗核心抗体筛查。
Vox Sang. 1978;34(2):77-80. doi: 10.1111/j.1423-0410.1978.tb03726.x.
2
Hepatitis B core antibody in volunteer blood donors: comparison of radioimmunoassay and indirect immunofluorescence.
J Med Virol. 1979;3(4):275-80. doi: 10.1002/jmv.1890030405.
3
Type B hepatitis after transfusion with blood containing antibody to hepatitis B core antigen.输注含有乙型肝炎核心抗原抗体的血液后发生的乙型肝炎。
N Engl J Med. 1978 Jun 22;298(25):1379-83. doi: 10.1056/NEJM197806222982502.
4
[Post-transfusional hepatitis in the city of Campinas, SP, Brazil. II. Presence of anti-HBc and anti-HCV antibodies in blood donor candidates and occurrence of post-transfusional hepatitis C in recipients of blood or derivates].[巴西圣保罗州坎皮纳斯市的输血后肝炎。II. 献血候选者中抗-HBc和抗-HCV抗体的存在情况以及血液或其衍生物接受者中输血后丙型肝炎的发生情况]
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Hepatitis B serology in Greek prostitutes: significance of the different serum markers.希腊妓女的乙肝血清学:不同血清标志物的意义
J Hyg (Lond). 1980 Apr;84(2):257-61. doi: 10.1017/s0022172400026759.
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Prevention of posttransfusion hepatitis B and C by screening for antibody to hepatitis C virus and antibody to HBcAg.通过筛查丙型肝炎病毒抗体和乙肝核心抗原抗体预防输血后乙型和丙型肝炎。
Hepatology. 1993 Nov;18(5):1045-9.
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Performance of an algorithm for the reentry of volunteer blood donors deferred due to false-positive test results for antibody to hepatitis B core antigen.针对因乙型肝炎核心抗原抗体检测结果假阳性而延期的志愿献血者重新招募算法的性能。
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[Studies on hepatitis B virus infection in blood donors with positive anti-HBc and negative HBsAg].抗-HBc阳性且HBsAg阴性献血者的乙型肝炎病毒感染研究
Zhonghua Yu Fang Yi Xue Za Zhi. 1998 Jan;32(1):7-9.
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Anti-HBc & HBV-DNA detection in blood donors negative for hepatitis B virus surface antigen in reducing risk of transfusion associated HBV infection.对乙型肝炎病毒表面抗原阴性的献血者进行抗-HBc及HBV-DNA检测以降低输血相关HBV感染风险。
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Significance of screening antibodies to hepatitis B virus core antigen among Syrian blood donors.叙利亚献血者中乙肝病毒核心抗原筛查抗体的意义
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引用本文的文献

1
The value of screening blood donors for antibody to hepatitis B core antigen.筛查献血者乙型肝炎核心抗原抗体的价值。
J Clin Pathol. 1983 Aug;36(8):924-8. doi: 10.1136/jcp.36.8.924.
2
Anti-HBc screening for the prevention of perinatal transmission of hepatitis B virus in France.法国预防乙型肝炎病毒围产期传播的抗-HBc筛查
Infection. 1987 Nov-Dec;15(6):434-9. doi: 10.1007/BF01647225.
3
Blood transfusion and hepatitis: still a threat?输血与肝炎:仍是一种威胁?
Blut. 1989 Jan;58(1):1-6. doi: 10.1007/BF00320227.
4
Serological evidence of presence of HBsAg undetectable by conventional radioimmunoassay in anti-HBc positive blood donors.抗-HBc阳性献血者中存在常规放射免疫测定法检测不到的HBsAg的血清学证据。
J Clin Pathol. 1978 Sep;31(9):837-9. doi: 10.1136/jcp.31.9.837.