Scheifele D W, Smith A L
Am J Dis Child. 1978 Jan;132(1):46-8. doi: 10.1001/archpedi.1978.02120260048013.
Follow-up of children with recurrent urinary infections would be simplified by an accurate home-testing program for detection of infection. We provided nitrite test strips to the parents of 30 girls with recurrent urinary infection to determine if twice weekly home testing of first-voided urine could reliably detect infection. Infections were documented by dip slides or colony counts indicating more than 10(5) bacteria per milliliter of urine. Twenty-four families (80%) complied over a mean study period of 11 months, detecting 28 of 30 episodes of bacteriuria (93%). No false-positive tests occurred. Urinary nitrate, the substrate for nitrite production by bacteria, was universally present (greater than 100 microgram/ml) in 80 children. The nitrite test is useful for home follow-up observation of children at high risk of bacteriuria if applied repeatedly by motivated parents.
通过精确的家庭检测程序来检测感染，可简化复发性泌尿道感染儿童的随访工作。我们为30名复发性泌尿道感染女童的家长提供了亚硝酸盐试纸，以确定每周对晨尿进行两次家庭检测能否可靠地检测出感染。通过浸片或菌落计数记录感染情况，即每毫升尿液中细菌超过10⁵个。在平均11个月的研究期间，24个家庭（80%）配合检测，检测出30例菌尿症中的28例（93%）。未出现假阳性检测结果。尿液硝酸盐作为细菌产生亚硝酸盐的底物，在80名儿童中普遍存在（大于100微克/毫升）。如果积极的家长反复应用亚硝酸盐检测，该检测对于菌尿症高危儿童的家庭随访观察很有用。
