体外筛选耐药菌群体后，西诺沙星、环丙沙星、DJ - 6783、依诺沙星、萘啶酸、诺氟沙星和恶喹酸之间的交叉耐药性。
Cross-resistance among cinoxacin, ciprofloxacin, DJ-6783, enoxacin, nalidixic acid, norfloxacin, and oxolinic acid after in vitro selection of resistant populations.
作者信息
Barry A L, Jones R N
出版信息
Antimicrob Agents Chemother. 1984 Jun;25(6):775-7. doi: 10.1128/AAC.25.6.775.
Abstract
Six different gram-negative bacilli were serially transferred through subinhibitory concentrations of seven quinolone derivatives or related organic acids. A gradual, stepwise decrease in susceptibility was noted with all seven drugs, and the resistant cultures demonstrated a concomitant cross-resistance to the other drugs.
摘要
六种不同的革兰氏阴性杆菌通过七种喹诺酮衍生物或相关有机酸的亚抑制浓度进行连续传代培养。所有七种药物的敏感性均出现逐渐、逐步下降，并且耐药培养物对其他药物表现出相应的交叉耐药性。
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本文引用的文献
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Pharmacokinetics and tissue penetration of ciprofloxacin.环丙沙星的药代动力学及组织穿透性
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Norfloxacin (MK-0366, AM-715): in vitro activity and cross-resistance with other organic acids including quality control limits for disk diffusion testing.诺氟沙星（MK - 0366，AM - 715）：体外活性及与其他有机酸的交叉耐药性，包括纸片扩散法检测的质量控制限度
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In vitro activity of enoxacin, a quinolone carboxylic acid, compared with those of norfloxacin, new beta-lactams, aminoglycosides, and trimethoprim.喹诺酮羧酸依诺沙星的体外活性与诺氟沙星、新型β-内酰胺类、氨基糖苷类及甲氧苄啶的体外活性比较。
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In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents.新型喹啉衍生物Bay 09867与其他抗菌药物的体外活性比较。
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