Jacque C M, Vinner C, Kujas M, Raoul M, Racadot J, Baumann N A
J Neurol Sci. 1978 Jan;35(1):147-55. doi: 10.1016/0022-510x(78)90107-7.
Brain tumors have been tested for their glial fibrillary acidic protein (GFAP) content by means of the rocket electrophoresis technique. Meningiomas and neurinomas were low in GFAP. Metastases had a low level of GFAP except when contaminated with surrounding tissue. Non-nervous tumors such as myeloma, myeloplaxoma and adenocarcinoma gave negative results. More detailed correlations with histological observations have been looked for in glial tumors. Low levels of GFAP were always associated with signs of malignancy such as mitoses and giant or atypical cells, whereas high levels of GFAP were correlated with the presence of well-preserved astrocytes.
已通过火箭电泳技术检测脑肿瘤的胶质纤维酸性蛋白（GFAP）含量。脑膜瘤和神经鞘瘤的GFAP含量较低。转移瘤的GFAP水平较低，除非被周围组织污染。骨髓瘤、髓母细胞瘤和腺癌等非神经肿瘤检测结果为阴性。在胶质瘤中已进一步寻找与组织学观察结果的详细相关性。GFAP低水平总是与恶性迹象相关，如有丝分裂以及巨细胞或非典型细胞，而GFAP高水平则与保存完好的星形胶质细胞的存在相关。
