Tabor E, Trichopoulos D, Manousos O, Zavitsanos X, Drucker J A, Gerety R J
Int J Epidemiol. 1980 Sep;9(3):221-3. doi: 10.1093/ije/9.3.221.
Serum samples from 77 caucasians of Greek origin with primary hepatocellular carcinoma (PHC) and 77 age- and sex-matched controls were tested for antibody to the hepatitis A virus (anti-HAV). Anti-HAV was detected in 63 patients with PHC (82%) and in 70 controls (91%). These data suggest that past infection with hepatitis A virus is not related to the development of PHC, in marked contrast to the strong association between PHC and HBV.
对77名患有原发性肝细胞癌(PHC)的希腊裔高加索人和77名年龄及性别匹配的对照者的血清样本进行了甲型肝炎病毒抗体(抗-HAV)检测。在63例PHC患者(82%)和70名对照者(91%)中检测到了抗-HAV。这些数据表明,既往甲型肝炎病毒感染与PHC的发生无关,这与PHC和HBV之间的强烈关联形成鲜明对比。