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甲型肝炎感染与原发性肝细胞癌

Hepatitis A infection and primary hepatocellular carcinoma.

作者信息

Drucker J A, Coursaget P, Maupas P, Goudeau A, Gerety R J, Chiron J P, Denis F, Diop Mar I

出版信息

Biomedicine. 1979 Feb;31(1):23-5.

PMID:224967
Abstract

The prevalence of antibody to the hepatitis A antigen (anti-HAV) has been studied in Senegal, among patients suffering from primary hepatocellular carcinoma (PHC) and among healthy blood donors. Anti-HAV was found in 62.5% of 64 cases of PHC as compared to 64% of 50 blood donors. Anti-HAV was as prevalent among PHC patients who evidenced chronic hepatitis B infection as among those without markers of chronic hepatitis B infection. These data suggest that hepatitis A infection is not associated with PHC in Senegal.

摘要

在塞内加尔,针对原发性肝细胞癌(PHC)患者以及健康献血者,开展了甲型肝炎抗原抗体(抗-HAV)流行情况的研究。在64例PHC患者中,62.5%检测出抗-HAV,而在50名健康献血者中,这一比例为64%。在有慢性乙型肝炎感染证据的PHC患者中,抗-HAV的流行率与无慢性乙型肝炎感染标志物的患者相当。这些数据表明,在塞内加尔,甲型肝炎感染与PHC无关。

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