Black R E, Merson M H, Rahman A S, Yunus M, Alim A R, Huq I, Yolken R H, Curlin G T
J Infect Dis. 1980 Nov;142(5):660-4. doi: 10.1093/infdis/142.5.660.
Enteric pathogens associated with diarrhea were studied for two years at a diarrhea treatment center in rural Bangladesh. Enterotoxigenic Escherichia coli (ETEC) was the most frequently identified pathogen for patients of all ages. Rotavirus and ETEC were isolated from approximately 50% and approximately 25%, respectively, of patients less than two years of age. A bacterial or viral pathogen was identified for 70% of these young children and for 56% of all patients with diarrhea. Most ETEC isolates were obtained in the hot dry months of March and April and the hot wet months of August and September. Rotavirus identification peaked in the cool dry months of December and January, but infected patients were found year-round. The low case-fatality rates for patients with watery diarrhea and substantial dehydration further document the usefulness of treating patients with diarrhea with either a glucose- or sucrose-base electrolyte solution such as those used in this treatment center.
在孟加拉国农村的一个腹泻治疗中心,对与腹泻相关的肠道病原体进行了为期两年的研究。产肠毒素大肠杆菌(ETEC)是所有年龄段患者中最常鉴定出的病原体。轮状病毒和ETEC分别从约50%和约25%的两岁以下患者中分离出来。在这些幼儿中,70%鉴定出了细菌或病毒病原体,在所有腹泻患者中这一比例为56%。大多数ETEC分离株是在3月和4月炎热干燥的月份以及8月和9月炎热潮湿的月份获得的。轮状病毒鉴定在12月和1月凉爽干燥的月份达到峰值,但全年都发现有感染患者。水样腹泻和严重脱水患者的低病死率进一步证明了使用该治疗中心所使用的基于葡萄糖或蔗糖的电解质溶液治疗腹泻患者的有效性。