Llinás R, Steinberg I Z, Walton K
Biophys J. 1981 Mar;33(3):323-51. doi: 10.1016/S0006-3495(81)84899-0.
The relationship between calcium current and transmitter release was studied in squid giant synapse. It was found that the voltage-dependent calcium current triggers the release of synaptic transmitter in direct proportion to its magnitude and duration. Transmitter release occurs with a delay of approximately 200 mus after the influx of calcium. A model is presented which describes these relations formally.
在枪乌贼巨大突触中研究了钙电流与递质释放之间的关系。发现电压依赖性钙电流触发突触递质的释放,其释放量与钙电流的大小和持续时间成正比。钙内流后约200微秒会出现递质释放。提出了一个正式描述这些关系的模型。