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原发性免疫球蛋白缺乏症中的埃可病毒脑炎和肌炎

Echovirus encephalitis and myositis in primary immunoglobulin deficiency.

作者信息

Webster A D, Tripp J H, Hayward A R, Dayan A D, Doshi R, Macintyre E H, Tyrrell D A

出版信息

Arch Dis Child. 1978 Jan;53(1):33-7. doi: 10.1136/adc.53.1.33.

DOI:10.1136/adc.53.1.33
PMID:626516
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1544838/
Abstract

Two children are described with primary hypogammaglobulinaemia and encephalitis associated with echovirus infection. One also developed a condition resembling dermatomyositis which improved after he was given infusions of plasma containing antibody to the echovirus. Although both died of their encephalitis, the course of the brain disease in one of them may have been prolonged by treatment with specific antibody. These cases, together with another briefly mentioned case in an adult with congenital hypogammaglobulinaemia and echovirus infection, indicate that these patients are particularly susceptible to echoviruses.

摘要

本文描述了两名患有原发性低丙种球蛋白血症并伴有与埃可病毒感染相关的脑炎的儿童。其中一名儿童还出现了类似皮肌炎的病症,在输注含有抗埃可病毒抗体的血浆后病情有所改善。尽管两人均死于脑炎,但其中一人的脑部疾病病程可能因特异性抗体治疗而延长。这些病例,连同另一例简要提及的患有先天性低丙种球蛋白血症并感染埃可病毒的成人病例,表明这些患者对埃可病毒特别易感。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c850/1544838/53c60777d832/archdisch00809-0040-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c850/1544838/53c60777d832/archdisch00809-0040-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c850/1544838/53c60777d832/archdisch00809-0040-a.jpg

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1
Echovirus encephalitis and myositis in primary immunoglobulin deficiency.原发性免疫球蛋白缺乏症中的埃可病毒脑炎和肌炎
Arch Dis Child. 1978 Jan;53(1):33-7. doi: 10.1136/adc.53.1.33.
2
[Echovirus encephalitis during Bruton disease. Favorable development. Therapeutic problems].[布鲁顿病期间的埃可病毒脑炎。病情良好发展。治疗问题]
Arch Fr Pediatr. 1979 Jun;36(6):587-91.
3
Fatal ECHO 24 infection in a patient with hypogammaglobulinemia: relationship to dermatomyositis-like syndrome.一名低丙种球蛋白血症患者发生的致命性ECHO 24感染:与皮肌炎样综合征的关系。
J Pediatr. 1977 Mar;90(3):396-99. doi: 10.1016/s0022-3476(77)80700-2.
4
Intraventricular gamma-globulin for the management of enterovirus encephalitis.脑室内注射γ-球蛋白治疗肠道病毒脑炎
Pediatr Infect Dis J. 1988 May;7(5 Suppl):S30-3.
5
Persistent and fatal central-nervous-system ECHOvirus infections in patients with agammaglobulinemia.无丙种球蛋白血症患者中持续性和致命性的中枢神经系统埃可病毒感染。
N Engl J Med. 1977 Jun 30;296(26):1485-9. doi: 10.1056/NEJM197706302962601.
6
Echovirus encephalitis/myositis in X-linked agammaglobulinemia.X连锁无丙种球蛋白血症中的埃可病毒脑炎/肌炎
N Engl J Med. 1985 Sep 19;313(12):758. doi: 10.1056/nejm198509193131216.
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Effect of specific antibodies on chronic echovirus type 5 encephalitis in a patient with hypogammaglobulinemia.特异性抗体对一名低丙种球蛋白血症患者慢性埃可病毒5型脑炎的影响。
J Infect Dis. 1979 Dec;140(6):858-63. doi: 10.1093/infdis/140.6.858.
8
Successful treatment of echovirus meningoencephalitis and myositis-fasciitis with intravenous immune globulin therapy in a patient with X-linked agammaglobulinemia.静脉注射免疫球蛋白治疗X连锁无丙种球蛋白血症患者的埃可病毒脑膜脑炎和肌炎-筋膜炎取得成功。
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Successful reversal of echovirus encephalitis in X-linked hypogammaglobulinemia by intraventricular administration of immunoglobulin.通过脑室内注射免疫球蛋白成功逆转X连锁低丙种球蛋白血症患者的肠道病毒脑炎。
N Engl J Med. 1985 Feb 7;312(6):351-3. doi: 10.1056/NEJM198502073120605.
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Lower anti-echovirus antibody responses in children presenting to hospital with asthma exacerbations.因哮喘急性发作入院的儿童抗埃可病毒抗体反应较低。
Clin Exp Allergy. 2015 Oct;45(10):1523-30. doi: 10.1111/cea.12501.

引用本文的文献

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Non-pyogenic focal encephalitis diagnosis and follow-up by computed tomography and nuclear brain scanning.通过计算机断层扫描和脑核扫描进行非化脓性局灶性脑炎的诊断及随访。
Neuroradiology. 1980;20(3):155-8. doi: 10.1007/BF00341780.
2
HLA restriction of human cytotoxic T cells.人类细胞毒性T细胞的HLA限制
Springer Semin Immunopathol. 1980 May;3(1):3-22. doi: 10.1007/BF00199923.
3
Progressive spastic paraplegia due to persistent echo virus encephalomyelitis in a child with X-linked hypogammaglobulinaemia.一名患有X连锁低丙种球蛋白血症的儿童因持续性埃可病毒脑脊髓炎导致进行性痉挛性截瘫。

本文引用的文献

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Collagen disease in patients with congenital agammaglobulinemia.先天性无丙种球蛋白血症患者的胶原病
Trans Assoc Am Physicians. 1956;69:93-7.
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Chronic encephalitis in children with severe immuno-deficiency.重度免疫缺陷儿童的慢性脑炎
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Failure of intraventricular gammaglobulin and alpha interferon for persistent encephalitis in congenital hypogammaglobulinaemia.先天性低丙种球蛋白血症患者持续性脑炎使用脑室内注射丙种球蛋白和α干扰素治疗失败。
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Role of the virology laboratory in diagnosis and management of patients with central nervous system disease.病毒学实验室在中枢神经系统疾病患者诊断与管理中的作用。
Clin Microbiol Rev. 1989 Jan;2(1):1-14. doi: 10.1128/CMR.2.1.1.
9
Infective conjunctivitis and corneal scarring in three brothers with sex linked hypogammaglobulinaemia (Bruton's disease).三名患有性联低丙种球蛋白血症(布鲁顿氏病)的兄弟出现感染性结膜炎和角膜瘢痕形成。
Br J Ophthalmol. 1990 Feb;74(2):118-20. doi: 10.1136/bjo.74.2.118.
10
Impact on routine diagnosis of echovirus infections of intratypic differentiation and antigenic variation in echovirus type 25 studied by using monoclonal antibodies.使用单克隆抗体研究25型埃可病毒的型内分化和抗原变异对埃可病毒感染常规诊断的影响。
J Clin Microbiol. 1990 Oct;28(10):2291-6. doi: 10.1128/jcm.28.10.2291-2296.1990.
Clin Exp Immunol. 1973 May;14(1):25-35.
4
Subacute encephalitis and hypogammaglobulinemia.亚急性脑炎和低丙种球蛋白血症
Am J Dis Child. 1972 Feb;123(2):151-5. doi: 10.1001/archpedi.1972.02110080129017.
5
Dermatomyositis with cerebral vasculitis in a patient with agammaglobulinemia.无丙种球蛋白血症患者伴发脑动脉炎的皮肌炎
Am J Dis Child. 1972 Jan;123(1):53-6. doi: 10.1001/archpedi.1972.02110070103015.
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Migration inhibition test in leukocytes from patients allergic to penicillin.对青霉素过敏患者白细胞的迁移抑制试验
J Immunol. 1974 Sep;113(3):993-7.
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Fatal viral encephalitis in children with X-linked hypogammaglobulinemia.患有X连锁低丙种球蛋白血症儿童的致命性病毒性脑炎。
Am J Dis Child. 1973 Jul;126(1):100-3. doi: 10.1001/archpedi.1973.02110190088019.
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Dichotomy between immunoglobulin synthesis by cells in gut and blood of patients with hypogammaglobulinaemia.低丙种球蛋白血症患者肠道和血液中细胞免疫球蛋白合成的二分法。
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Fatal echo 30 virus infection and amyloidosis in X-linked hypogammaglobulinemia.X连锁低丙种球蛋白血症中的致死性埃可30病毒感染与淀粉样变性
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