Kanao M, Itoh M, Yamamoto T, Okada H
Jpn J Antibiot. 1981 Apr;34(4):515-20.
Fundamental and clinical studies were made on cefotaxime (HR-756, CTX), a new cephalosporin antibiotic, with the following results. 1. Cefotaxime was given to 22 patients. Efficacy was excellent in 3 cases, good in 17 cases and poor in 2 cases. No side effects were observed in any cases. 2. Following a single intravenous injection of 1.0 or 2.0 g, the transfer of CTX to the internal genital organs was found to be good. The transfer of CTX to exudate of the dead space of pelvis was also good. 3. The above data demonstrated that CTX is a safe and effective drug.
对新型头孢菌素抗生素头孢噻肟（HR - 756，CTX）进行了基础和临床研究，结果如下。1. 对22例患者使用了头孢噻肟。疗效极佳的有3例，良好的有17例，不佳的有2例。所有病例均未观察到副作用。2. 单次静脉注射1.0克或2.0克后，发现CTX向生殖内器官的转移良好。CTX向盆腔死腔渗出液的转移也良好。3. 上述数据表明CTX是一种安全有效的药物。
