Horii T, Ikeda M, Okumura Y, Teshima K, Noda K
Jpn J Antibiot. 1984 Dec;37(12):2364-70.
Fundamental and clinical studies on ceftriaxone (Ro 13-9904, CTRX), a new cephem antibiotic, were carried out with the following results. Following each 1.0 g of drip infusion, transfer of CTRX to female genital organs was found to be excellent. Transfer of CTRX to exudate of the pelvic dead space was also excellent. And high concentration of CTRX was kept for long time after administration. CTRX was given to 7 cases. It was effective for 5 cases and ineffective for 2 cases. The above results demonstrated that CTRX is a safe and effective drug.
对新型头孢菌素抗生素头孢曲松（Ro 13-9904，CTRX）进行了基础和临床研究，结果如下。每次静脉滴注1.0克后，发现CTRX向女性生殖器官的转移情况良好。CTRX向盆腔死腔渗出液的转移情况也良好。给药后CTRX能长时间保持高浓度。对7例患者使用了CTRX。其中5例有效，2例无效。上述结果表明CTRX是一种安全有效的药物。
