Lee S H, Zucker M, Sato T
Hum Pathol. 1981 Nov;12(11):1034-7. doi: 10.1016/s0046-8177(81)80263-8.
A case of primary mucinous (colloid) adenocarcinoma associated with multiple perianal fistulas and a supra-anal intergluteal abscess of a short duration is described. The origin of this tumor has been much debated. Some believe that the tumor occurs primarily in an anal duct or its glands with secondary fistula formation, whereas others claim that the tumor arises in a chronic fistulous tract. The present study substantiates the former concept on the basis of the mode of clinical presentation and the pathologic findings of a large tumor, without involvement of the anorectal mucosa. The residual anal ducts and glands were found in close relationship with the tumor.
本文描述了一例原发性黏液性(胶样)腺癌,伴有多个肛周瘘管和病程较短的肛上臀间脓肿。该肿瘤的起源一直存在诸多争议。一些人认为肿瘤主要发生于肛管或其腺体,继而形成继发性瘘管,而另一些人则声称肿瘤起源于慢性瘘管。本研究基于临床表现方式及一个未累及肛门直肠黏膜的大肿瘤的病理发现,证实了前一种观点。发现残留的肛管和腺体与肿瘤关系密切。