无肾患者使用肌肉松弛剂阿曲库铵：初步报告
Use of the muscle relaxant atracurium in anephric patients: preliminary communication.
作者信息
Hunter J M, Jones R S, Utting J E
出版信息
J R Soc Med. 1982 May;75(5):336-40. doi: 10.1177/014107688207500509.
Abstract
Atracurium is a new, non-depolarizing muscle relaxant which rapidly breaks down in vivo and appears to require neither renal nor hepatic function for its elimination. As the commonly used non-depolarizing muscle relaxants carry the risk of prolonged effect when used in anephric patients, atracurium appears to have special promise in this situation. A preliminary account of the successful use of the relaxant in 20 anephric patients is recorded and evidence presented that atracurium is, indeed, a suitable agent for use in patients with renal failure.
摘要
阿曲库铵是一种新型非去极化肌松药，在体内迅速分解，其消除似乎既不依赖肾功能也不依赖肝功能。由于常用的非去极化肌松药用于无肾患者时有延长作用的风险，阿曲库铵在这种情况下似乎有特殊的应用前景。本文记录了该药在20例无肾患者中成功应用的初步情况，并提供证据表明阿曲库铵确实是适用于肾衰竭患者的药物。
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Use of the muscle relaxant atracurium in anephric patients: preliminary communication.无肾患者使用肌肉松弛剂阿曲库铵：初步报告
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引用本文的文献
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Evaluation of atracurium in anaesthetized man.阿曲库铵在麻醉人体中的评估。
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The pharmacology of atracurium: a new competitive neuromuscular blocking agent.阿曲库铵的药理学：一种新型竞争性神经肌肉阻滞剂。
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Br J Anaesth. 1970 Mar;42(3):235-48. doi: 10.1093/bja/42.3.235.
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The effect of tubocurarine on indirectly elicited train-of-four muscle response and respiratory measurements in humans.筒箭毒碱对人体间接诱发的四个成串肌肉反应及呼吸测量的影响。
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Anaesthesia. 1977 Mar;32(3):247-51. doi: 10.1111/j.1365-2044.1977.tb11602.x.
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