鸟苷对小鼠甲型流感感染的利巴韦林气雾剂治疗无干扰作用。
Lack of interference of guanosine with ribavirin aerosol treatment of influenza A infection in mice.
作者信息
Knight V, Wilson S Z, Alling D W, Moore R V, Longoria R M
出版信息
Antimicrob Agents Chemother. 1981 Oct;20(4):477-80. doi: 10.1128/AAC.20.4.477.
Abstract
Guanosine or guanosine 5'-monophosphate did not reduce the protective effect of ribavirin aerosol in influenza virus A/Aichi/68 H3N2 infection of mice. Both compounds partially interfered with the action of a wide range of ribavirin concentrations against influenza virus A/WSN replication in cell culture.
摘要
鸟苷或5'-单磷酸鸟苷不会降低利巴韦林气雾剂对甲型/爱知/68 H3N2流感病毒感染小鼠的保护作用。这两种化合物都部分干扰了多种浓度的利巴韦林在细胞培养中对甲型/WSN流感病毒复制的作用。
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