巨细胞病毒感染的人成纤维细胞中肌动蛋白的分布与合成
Actin distribution and synthesis in human fibroblasts infected by cytomegalovirus.
作者信息
Lösse D, Lauer R, Weder D, Radsak K
出版信息
Arch Virol. 1982;71(4):353-9. doi: 10.1007/BF01315066.
PMID:6284094
Abstract
"Early functions" of human cytomegalovirus were found to induce a loss of microfilaments as revealed by indirect immunofluorescence and by the use of fluorescent phalloidin. Actin synthesis in infected cultures, on the other hand, appeared to be largely unchanged as estimated from the specific radioactivity of cytoplasmic actin.
摘要
人巨细胞病毒的“早期功能”被发现可诱导微丝丢失，这通过间接免疫荧光和使用荧光鬼笔环肽得以揭示。另一方面，根据细胞质肌动蛋白的比放射性估计，感染培养物中的肌动蛋白合成似乎基本未变。
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