Wolff M H, Zoll A, Schneweis K E
Med Microbiol Immunol. 1982;170(4):241-6. doi: 10.1007/BF02123314.
In Herpes simplex virus (HSV) infected cells treated with the arginine analogue canavanine, early (alpha -) viral proteins accumulate and show a typical pattern in the acrylamide gel. This paper investigates the possibility of using this pattern for typing of HSV strains. Twenty strains were analyzed by this method and results were compared with typing by neutralization test. For 18 strains both methods agreed. Two strains regarded as intermediary strains by neutralization test could be clearly typed by the analysis of the early proteins.
在用精氨酸类似物刀豆氨酸处理的单纯疱疹病毒（HSV）感染细胞中，早期（α -）病毒蛋白会积累，并在丙烯酰胺凝胶中呈现出典型模式。本文研究了利用这种模式对HSV毒株进行分型的可能性。通过该方法分析了20个毒株，并将结果与中和试验分型结果进行比较。对于18个毒株，两种方法的结果一致。中和试验视为中间毒株的两个毒株，通过早期蛋白分析能够明确分型。
