Keane F B, O'Connor M, Stephens R B, Freyne P J, Hennessy T P
Br J Surg. 1982 Jul;69(7):383-5. doi: 10.1002/bjs.1800690709.
Following intravenous injection, technetium-99m (99Tcm) is selectively taken up by the stomach, and this uptake, which is stimulated by pentagastrin, may be quantified using a gamma camera. Using this property of 99Tcm as a means of assessing gastric function, we found that the mean rate of 99Tcm uptake was significantly greater in 24 duodenal ulcer patients than in 10 healthy controls (P less than 0.01). Scanning values did not correlate with BAO of MAO which were measured on a separate day. Both vagotomy (n = 10) and cimetidine infusion (n = 5) significantly reduced the rate of uptake of 99Tcm (P less than 0.01). Thus, although 99Tcm reflects a function of the stomach which is similar to acid secretion, scanning did not give a good estimate of acid secretion in this group of subjects.
静脉注射后，锝-99m（99Tcm）被胃选择性摄取，这种由五肽胃泌素刺激的摄取可使用γ相机进行定量。利用99Tcm的这一特性作为评估胃功能的手段，我们发现24例十二指肠溃疡患者的99Tcm平均摄取率显著高于10例健康对照者（P<0.01）。扫描值与在另一天测量的基础胃酸分泌量（BAO）或最大胃酸分泌量（MAO）无关。迷走神经切断术（n = 10）和西咪替丁输注（n = 5）均显著降低了99Tcm的摄取率（P<0.01）。因此，尽管99Tcm反映的胃功能与胃酸分泌相似，但在这组受试者中，扫描并不能很好地估计胃酸分泌情况。
