白细胞介素1对培养的成纤维细胞产生胶原酶的刺激作用。
Interleukin 1 stimulation of collagenase production by cultured fibroblasts.
作者信息
Postlethwaite A E, Lachman L B, Mainardi C L, Kang A H
出版信息
J Exp Med. 1983 Feb 1;157(2):801-6. doi: 10.1084/jem.157.2.801.
Abstract
Interleukin 1 is a monokine that exerts biological effects on a variety of target cells in vitro. In this report, interleukin 1 has been found to be capable of stimulating collagenase production by cultured dermal fibroblasts. The concentrations of interleukin 1 that stimulate fibroblast collagenase production are similar to those that stimulate mouse thymocyte proliferation. Analyses by high performance liquid chromatography indicate that interleukin 1, rather than a contaminating monokine, is responsible for this effect on fibroblasts. Interleukin 1, released in vivo by macrophages infiltrating sites of tissue damage or inflammation, may function to stimulate the release of collagenase by connective tissue fibroblasts.
摘要
白细胞介素1是一种单核因子，在体外对多种靶细胞发挥生物学效应。在本报告中，已发现白细胞介素1能够刺激培养的真皮成纤维细胞产生胶原酶。刺激成纤维细胞胶原酶产生的白细胞介素1浓度与刺激小鼠胸腺细胞增殖的浓度相似。高效液相色谱分析表明，对成纤维细胞产生这种作用的是白细胞介素1，而非污染性单核因子。浸润组织损伤或炎症部位的巨噬细胞在体内释放的白细胞介素1，可能起到刺激结缔组织成纤维细胞释放胶原酶的作用。
相似文献
1
Interleukin 1 stimulation of collagenase production by cultured fibroblasts.白细胞介素1对培养的成纤维细胞产生胶原酶的刺激作用。
J Exp Med. 1983 Feb 1;157(2):801-6. doi: 10.1084/jem.157.2.801.
2
Lyme disease spirochetes induce human and murine interleukin 1 production.莱姆病螺旋体可诱导人和小鼠产生白细胞介素1。
J Immunol. 1985 May;134(5):3147-54.
3
Modulation of fibroblast functions by interleukin 1: increased steady-state accumulation of type I procollagen messenger RNAs and stimulation of other functions but not chemotaxis by human recombinant interleukin 1 alpha and beta.白细胞介素1对成纤维细胞功能的调节作用：人重组白细胞介素1α和β可增加I型前胶原信使核糖核酸的稳态积累，并刺激其他功能，但不影响趋化性。
J Cell Biol. 1988 Feb;106(2):311-8. doi: 10.1083/jcb.106.2.311.
4
An interleukin 1 inhibitor affects both cell-associated interleukin 1-induced T cell proliferation and PGE2/collagenase production by human dermal fibroblasts and synovial cells.一种白细胞介素-1抑制剂可影响与细胞相关的白细胞介素-1诱导的T细胞增殖，以及人皮肤成纤维细胞和滑膜细胞产生前列腺素E2/胶原酶的过程。
Immunobiology. 1990 Jun;180(4-5):316-27. doi: 10.1016/S0171-2985(11)80295-0.
5
Presence of epidermal-derived thymocyte activating factor/interleukin 1 in normal human stratum corneum.正常人角质层中存在表皮来源的胸腺细胞活化因子/白细胞介素1 。
J Clin Invest. 1985 Oct;76(4):1585-91. doi: 10.1172/JCI112141.
6
Modulation of IL-1 inflammatory and immunomodulatory properties by IL-6.
Eur Cytokine Netw. 1991 Jan-Feb;2(1):39-46.
7
Interleukin-1 beta- and tumor necrosis factor-alpha-independent monocyte stimulation of fibroblast collagenase activity.白细胞介素-1β和肿瘤坏死因子-α非依赖性单核细胞对成纤维细胞胶原酶活性的刺激
J Cell Biochem. 1990 Dec;44(4):253-64. doi: 10.1002/jcb.240440407.
8
9
Induction of fibroblast proliferation by interleukin-1 derived from human monocytic leukemia cells.源自人单核细胞白血病细胞的白细胞介素-1对成纤维细胞增殖的诱导作用。
Arthritis Rheum. 1984 Sep;27(9):995-1001. doi: 10.1002/art.1780270905.
10
Cultured human alveolar macrophages from smokers with lung cancer: resolution of factors that stimulate fibroblast proliferation, production of collagenase, or prostaglandin E2.
J Leukoc Biol. 1985 May;37(5):641-9. doi: 10.1002/jlb.37.5.641.
引用本文的文献
1
Candidate gene polymorphisms associated with silicosis and coal workers' pneumoconiosis: a systematic review and meta-analysis.候选基因多态性与矽肺和煤工尘肺的关系：系统评价和荟萃分析。
BMC Pulm Med. 2024 Nov 22;24(1):580. doi: 10.1186/s12890-024-03392-0.
2
Crosstalk between fibroblasts and immunocytes in fibrosis: From molecular mechanisms to clinical trials.成纤维细胞与免疫细胞在纤维化中的相互作用：从分子机制到临床试验。
Clin Transl Med. 2024 Jan;14(1):e1545. doi: 10.1002/ctm2.1545.
3
What Is IL-1 for? The Functions of Interleukin-1 Across Evolution.IL-1 是做什么的？白细胞介素-1 在进化中的功能。
Front Immunol. 2022 Apr 6;13:872155. doi: 10.3389/fimmu.2022.872155. eCollection 2022.
4
Pathogenesis and Bone Resorption in Acquired Cholesteatoma: Current Knowledge and Future Prospectives.获得性胆脂瘤的发病机制与骨吸收：当前认知与未来展望
Clin Exp Otorhinolaryngol. 2016 Dec;9(4):298-308. doi: 10.21053/ceo.2015.01662. Epub 2016 Jul 21.
5
The imbalance between metalloproteinases and their tissue inhibitors is involved in the pathogenesis of dermatitis herpetiformis.金属蛋白酶与其组织抑制剂之间的失衡参与疱疹样皮炎的发病机制。
Mediators Inflamm. 2005 Dec 14;2005(6):373-9. doi: 10.1155/MI.2005.373.
6
High expression of interleukin-1beta in the corneal epithelium of MRL/lpr mice is under the control of their genetic background.白细胞介素-1β在MRL/lpr小鼠角膜上皮中的高表达受其遗传背景的控制。
Clin Exp Immunol. 2004 May;136(2):239-44. doi: 10.1111/j.1365-2249.2004.02428.x.
7
Glucocorticoid receptor-mediated suppression of activator protein-1 activation and matrix metalloproteinase expression after spinal cord injury.脊髓损伤后糖皮质激素受体介导的激活蛋白-1激活抑制及基质金属蛋白酶表达抑制
J Neurosci. 2001 Jan 1;21(1):92-7. doi: 10.1523/JNEUROSCI.21-01-00092.2001.
8
Organising pneumonia.机化性肺炎
Thorax. 2000 Apr;55(4):318-28. doi: 10.1136/thorax.55.4.318.
9
Cytokines in asthma.哮喘中的细胞因子。
Thorax. 1999 Sep;54(9):825-57. doi: 10.1136/thx.54.9.825.
10
Role of fibroblasts in the regulation of proinflammatory interleukin IL-1, IL-6 and IL-8 levels induced by keratinocyte-derived IL-1.成纤维细胞在调节角质形成细胞衍生的白细胞介素-1诱导的促炎白细胞介素-1、白细胞介素-6和白细胞介素-8水平中的作用
Arch Dermatol Res. 1996 Jun;288(7):391-8. doi: 10.1007/BF02507108.
本文引用的文献
1
2
Lymphokines: their role in lymphocyte responses. Properties of interleukin 1.淋巴因子：它们在淋巴细胞反应中的作用。白细胞介素1的特性。
Fed Proc. 1982 Feb;41(2):257-62.
3
Purification of human interleukin 1.人白细胞介素1的纯化
J Supramol Struct. 1980;13(4):457-66. doi: 10.1002/jss.400130405.
4
Interleukin 1, a potential regulator of fibroblast proliferation.白细胞介素1，一种成纤维细胞增殖的潜在调节因子。
J Immunol. 1982 May;128(5):2177-82.
5
Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).部分纯化的淋巴细胞激活因子（白细胞介素1）对类风湿性滑膜细胞胶原酶和前列腺素产生的刺激作用。
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2474-7. doi: 10.1073/pnas.78.4.2474.
6
A quantitative collagen film collagenase assay for large numbers of samples.一种用于大量样本的定量胶原膜胶原酶检测方法。
Anal Biochem. 1980 May 1;104(1):175-81. doi: 10.1016/0003-2697(80)90295-x.
7
Antigen-nonspecific helper factors in the antibody response.抗体应答中的抗原非特异性辅助因子。
Fed Proc. 1982 Feb;41(2):263-8.
8
Preparation of lymphocyte-activating factor from continuous murine macrophage cell lines.从连续的小鼠巨噬细胞系制备淋巴细胞激活因子。
Cell Immunol. 1977 Dec;34(2):416-9. doi: 10.1016/0008-8749(77)90263-5.
9
Preparation and characterization of lymphocyte-activating factor (LAF) from acute monocytic and myelomonocytic leukemia cells.
Cell Immunol. 1978 Nov;41(1):199-206. doi: 10.1016/s0008-8749(78)80040-9.
10
Collagenase production by human synovial tissues.
Ann N Y Acad Sci. 1975 Jun 13;256:289-303. doi: 10.1111/j.1749-6632.1975.tb36056.x.
Zotero 插件