源自非洲爪蟾主要成年α-珠蛋白mRNA的克隆cDNA的完整核苷酸序列。
Complete nucleotide sequence of a cloned cDNA derived from the major adult alpha-globin mRNA of X. laevis.
作者信息
Kay R M, Harris R, Patient R K, Williams J G
出版信息
Nucleic Acids Res. 1983 Mar 11;11(5):1537-42. doi: 10.1093/nar/11.5.1537.
Abstract
The complete sequence of a cloned cDNA derived from the major adult alpha-globin mRNA of Xenopus laevis (the South African Clawed Toad) is presented. The sequence contains the complete coding and 3' non-coding regions of the mRNA and part of the 5' non-coding region. The amino acid sequence of the encoded alpha-globin polypeptide has been deduced and is compared to other alpha-globin polypeptides. We find that the sequence is equally diverged from a bullfrog tadpole alpha-globin polypeptide and human alpha-globin polypeptide suggesting that these three sequences may have diverged from a common ancestral sequence several hundred million years ago.
摘要
本文给出了从非洲爪蟾（南非爪蟾）主要成年α-珠蛋白mRNA克隆得到的cDNA的完整序列。该序列包含mRNA完整的编码区和3'非编码区以及部分5'非编码区。已推导编码的α-珠蛋白多肽的氨基酸序列，并与其他α-珠蛋白多肽进行了比较。我们发现该序列与牛蛙蝌蚪α-珠蛋白多肽和人α-珠蛋白多肽的差异程度相同，这表明这三个序列可能在几亿年前就从一个共同的祖先序列分化而来。
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本文引用的文献
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