氯乙烯接触工人皮肤毛细血管的体内观察。英美比较。
In vivo observations of skin capillaries in workers exposed to vinyl chloride. An English-American comparison.
作者信息
Maricq H R, Darke C S, Archibald R M, Leroy E C
出版信息
Br J Ind Med. 1978 Feb;35(1):1-7. doi: 10.1136/oem.35.1.1.
An unselected sample of vinyl chloride (VC)-exposed individuals, all employees of a polyvinyl chloride production plant in England (129 subjects), were examined by in vivo capillary microscopy. Results were compared with those previously obtained from a similar study in the USA to determine whether an association between VC exposure and capillary abnormalities could be found in different environments. The results showed a similar distribution of capillary abnormalities among the VC workers in both countries (39.5% in England compared with 36% in the USA). These capillary abnormalities were significantly more frequent among VC-exposed subjects than among control industrial workers (7.7%, 6%). In vivo microscopy also showed a higher incidence of papular lesions (13.5%) than had been detected clinically (1%).
对氯乙烯（VC）暴露个体的非选择性样本进行了研究，这些个体均为英国一家聚氯乙烯生产厂的员工（共129名受试者），采用活体毛细血管显微镜检查。将结果与之前在美国进行的类似研究结果进行比较，以确定在不同环境中是否能发现VC暴露与毛细血管异常之间的关联。结果显示，两国VC工人中毛细血管异常的分布相似（英国为39.5%，美国为36%）。这些毛细血管异常在VC暴露受试者中比在对照产业工人中明显更常见（分别为7.7%和6%）。活体显微镜检查还显示丘疹性病变的发生率（13.5%）高于临床检测到的发生率（1%）。
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