爱泼斯坦-巴尔病毒基因组中的成簇重复序列。
Clustered repeat sequences in the genome of Epstein Barr virus.
作者信息
Jones M D, Griffin B E
出版信息
Nucleic Acids Res. 1983 Jun 25;11(12):3919-37. doi: 10.1093/nar/11.12.3919.
Abstract
The genome of Epstein-Barr virus is composed of unique DNA interspersed with repetitive sequences. This organization suggests that Epstein-Barr virus provides a useful model for studying the function(s) of repetitive sequences in eukaryotic chromosomes. The primary structure of two of the repeat sequences, the 3072 bp large internal repeat, or BamHI-W repeat, and a smaller 125 bp, G, C-rich NotI repeat, are presented here. Their structures and possible functions are discussed.
摘要
爱泼斯坦-巴尔病毒的基因组由散布着重复序列的独特DNA组成。这种结构表明，爱泼斯坦-巴尔病毒为研究真核染色体中重复序列的功能提供了一个有用的模型。本文介绍了两个重复序列的一级结构，即3072 bp的大内部重复序列或BamHI-W重复序列，以及一个较小的125 bp富含G、C的NotI重复序列。讨论了它们的结构和可能的功能。
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