Anderson L W, Klevjer-Anderson P, Liggitt H D
Infect Immun. 1983 Aug;41(2):837-40. doi: 10.1128/iai.41.2.837-840.1983.
Permissiveness of blood-derived caprine monocytes to infection by caprine arthritis-encephalitis virus increased during in vitro cultivation and differentiation into macrophages, as evidenced by immunofluorescence and release of extracellular infectious virus. The degree of cell susceptibility to virus infection varied among individual goats, independent of age or breed. Caprine arthritis-encephalitis virus infection of macrophages in vitro resulted in no alteration of five characteristic functional activities.
血液来源的山羊单核细胞对山羊关节炎-脑炎病毒感染的易感性在体外培养和分化为巨噬细胞的过程中增加,这通过免疫荧光和细胞外感染性病毒的释放得以证明。细胞对病毒感染的易感性程度在不同的山羊个体间存在差异,与年龄或品种无关。体外山羊关节炎-脑炎病毒感染巨噬细胞并未导致五项特征性功能活动发生改变。