单纯疱疹病毒对兔肺泡巨噬细胞和腹腔巨噬细胞功能的影响
Alteration of rabbit alveolar and peritoneal macrophage function by herpes simplex virus.
作者信息
Plaeger-Marshall S, Wilson L A, Smith J W
出版信息
Infect Immun. 1983 Sep;41(3):1376-9. doi: 10.1128/iai.41.3.1376-1379.1983.
Abstract
Exposure of rabbit alveolar and peritoneal macrophages to infectious herpes simplex virus resulted in inhibition of antibody-dependent cellular cytotoxicity and either enhancement or inhibition of phagocytosis. At all times after exposure, virus was inhibitory to peritoneal macrophage phagocytosis. Alveolar macrophages showed enhanced phagocytic activity in the early stages of virus exposure and inhibition at later time points.
摘要
将兔肺泡巨噬细胞和腹腔巨噬细胞暴露于感染性单纯疱疹病毒后，会导致抗体依赖性细胞毒性受到抑制，吞噬作用增强或受到抑制。在暴露后的所有时间点，病毒均抑制腹腔巨噬细胞的吞噬作用。肺泡巨噬细胞在病毒暴露的早期阶段表现出吞噬活性增强，而在后期时间点则受到抑制。
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