Heller M, Henderson A, Kieff E
Proc Natl Acad Sci U S A. 1982 Oct;79(19):5916-20. doi: 10.1073/pnas.79.19.5916.
The third internal repeat (IR3) simple repeat array in Epstein-Barr virus (EBV) DNA has a high degree of homology to a reiterated component of cell DNAs. 32P-Labeled human or mouse DNAs hybridize to the IR3 sequence on Southern blots of viral DNA. EBV IR3 probe identifies many restriction enzyme fragments on Southern blots of human and mouse DNAs that have extensive homology to IR3. Cytological hybridization shows that IR3 is homologous to at least one region on each human chromosome except the Y chromosome.
爱泼斯坦-巴尔病毒(EBV)DNA中的第三个内部重复序列(IR3)简单重复阵列与细胞DNA的一个重复组分具有高度同源性。在病毒DNA的Southern印迹上,用32P标记的人或小鼠DNA与IR3序列杂交。EBV IR3探针在人及小鼠DNA的Southern印迹上可识别许多与IR3具有广泛同源性的限制性酶切片段。细胞杂交显示,IR3与除Y染色体外的每个人类染色体上的至少一个区域同源。