Almagro U A
Cancer. 1983 Oct 15;52(8):1453-7. doi: 10.1002/1097-0142(19831015)52:8<1453::aid-cncr2820520819>3.0.co;2-9.
Three cases of primary signet-ring carcinoma, or linitis plastica, of the colon are described. This rare form of colonic carcinoma possesses certain clinical, pathologic, and biologic characteristics that differ from those of the ordinary colorectal adenocarcinoma. Most importantly, the prognosis is poor, with only very few patients surviving more than one year following diagnosis. Some authors believe that the poor prognosis seen with this tumor may be due largely to a delay in diagnosis. Therefore, awareness of this form of colonic malignancy should be stressed so that early recognition may be made at a stage when curative treatment can still be instituted.
本文描述了3例原发性结肠印戒细胞癌或皮革胃。这种罕见的结肠癌形式具有某些临床、病理和生物学特征，与普通结直肠腺癌不同。最重要的是，预后很差，诊断后只有极少数患者存活超过一年。一些作者认为，这种肿瘤预后差可能主要是由于诊断延迟。因此，应强调对这种结肠恶性肿瘤形式的认识，以便在仍可进行根治性治疗的阶段尽早识别。
