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在传染性单核细胞增多症期间或之后,未能证明除爱泼斯坦-巴尔病毒(EBV)外对其他病毒抗原的伴随抗体变化。

Failure to demonstrate concomitant antibody changes to viral antigens other than Epstein-Barr virus (EBV) during or after infectious mononucleosis.

作者信息

Evans A S, Wanat J, Niederman J C

出版信息

Yale J Biol Med. 1983 May-Jun;56(3):203-9.

Abstract

A search for antibody rises to viral antigens other than to Epstein-Barr virus, the causative agent, has been carried out in serial serum samples from 82 patients with infectious mononucleosis (IM). Fourfold or greater rises in titer rarely occurred and did did not cluster in time. No rises occurred to cytomegalovirus, only 1.2 percent to herpes simplex virus, and 8.5 percent to varicella zoster virus. Rises to measles antibody were found in 7.5 percent of patients and to rubella in 10.4 percent; these may represent natural infections or immunizations. A few patients also showed rises to respiratory viruses but there was no apparent connection to IM.

摘要

对82例传染性单核细胞增多症(IM)患者的系列血清样本进行了检测,以寻找针对除致病因子爱泼斯坦-巴尔病毒之外的病毒抗原的抗体升高情况。滴度升高四倍或更高的情况很少发生,且在时间上没有聚集现象。巨细胞病毒抗体未升高,单纯疱疹病毒抗体升高的仅占1.2%,水痘带状疱疹病毒抗体升高的占8.5%。7.5%的患者麻疹抗体升高,10.4%的患者风疹抗体升高;这些可能代表自然感染或免疫接种。少数患者还显示出呼吸道病毒抗体升高,但与IM没有明显关联。

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本文引用的文献

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Infectious mononucleosis in an adult progressing to fatal immunoblastic lymphoma.
Ann Intern Med. 1982 Jun;96(6 Pt 1):737-42. doi: 10.7326/0003-4819-96-6-737.

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