Influence of cell cycle on the efficiency of transfection with purified human cytomegalovirus DNA.
作者信息
Musiani M, Zerbini M
出版信息
Arch Virol. 1983;78(3-4):287-92. doi: 10.1007/BF01311323.
PMID:6318698
Abstract
The efficiency of transfection of purified HCMV genome was studied in synchronized human embryo fibroblasts. The data show that HCMV DNA infection performed in S phase is more efficient than in cells infected in G2, M and G1 phases of cell cycle, respectively. These findings stress the importance of the metabolic state of cell cultures in HCMV genome transfection.
摘要
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