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多发性硬化症早中期的学习与记忆缺陷

Deficient learning and memory in early and middle phases of multiple sclerosis.

作者信息

Grant I, McDonald W I, Trimble M R, Smith E, Reed R

出版信息

J Neurol Neurosurg Psychiatry. 1984 Mar;47(3):250-5. doi: 10.1136/jnnp.47.3.250.

Abstract

Forty-three patients with multiple sclerosis showed disturbances in short-term memory, learning, and delayed recall which were associated with years of active disease (average was 4.5 years), age, presence of flareup, but not steroid/ACTH treatment. Unrecognised memory loss might be prevalent early in the natural history of multiple sclerosis and deserves neuropsychological assessment.

摘要

43例多发性硬化患者表现出短期记忆、学习及延迟回忆方面的障碍,这些障碍与多年的活动性疾病(平均4.5年)、年龄、病情发作有关,但与类固醇/促肾上腺皮质激素治疗无关。未被识别的记忆丧失在多发性硬化自然病程早期可能很普遍,值得进行神经心理学评估。

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