骨髓细胞促进肌肉再生与移植。
Muscle regeneration and transplantation enhanced by bone marrow cells.
作者信息
Meyer S, Yarom R
出版信息
Br J Exp Pathol. 1983 Feb;64(1):15-24.
Abstract
This work was undertaken in an attempt to improve the usually poor results of muscle regeneration and grafting in cases of muscle injury. Since bone marrow cells markedly increase myogenic growth in vitro (in Millipore diffusion chambers), we added autogenous and isologous bone marrow cells to minced muscle grafts or to sites of excised muscle in rats. In each case the opposite side was left without added marrow cells, to serve as a control. The results showed that addition of bone marrow produces more extensive muscle regeneration with little fibrosis. The myogenesis-stimulating and antibacterial properties of bone marrow cells warrant further study, aiming towards clinical application of the method.
摘要
本研究旨在改善肌肉损伤病例中通常较差的肌肉再生和移植效果。由于骨髓细胞在体外（在密理博扩散小室中）能显著促进肌源性生长，我们将自体和同种异体骨髓细胞添加到大鼠的肌肉碎块移植中或切除肌肉的部位。每种情况下，对侧不添加骨髓细胞作为对照。结果表明，添加骨髓可产生更广泛的肌肉再生且纤维化较少。骨髓细胞的促肌生成和抗菌特性值得进一步研究，以期该方法能应用于临床。
相似文献
1
Muscle regeneration and transplantation enhanced by bone marrow cells.骨髓细胞促进肌肉再生与移植。
Br J Exp Pathol. 1983 Feb;64(1):15-24.
2
[Reaction of intact skeletal muscle on the transplantation of minced muscle tissue].[完整骨骼肌对切碎肌肉组织移植的反应]
Biull Eksp Biol Med. 1986 Jan;101(1):81-4.
3
Secondary myogenesis of normal muscle produces abnormal myotubes.
Anat Rec. 1982 Nov;204(3):199-207. doi: 10.1002/ar.1092040304.
4
[An electron microscopic study of the regeneration process in minced muscle tissue in newborn rat pups].[新生大鼠幼崽肌肉组织切碎后的再生过程的电子显微镜研究]
Dokl Akad Nauk SSSR. 1991;316(6):1479-81.
5
Phagocytosis of necrotic muscle in muscle isografts is influenced by the strain, age, and sex of host mice.
J Pathol. 1987 Sep;153(1):71-82. doi: 10.1002/path.1711530110.
6
Transplant of bone marrow and muscle-derived connective tissue cultures in diffusion chambers for bioassay of bone morphogenetic protein.将骨髓和肌肉来源的结缔组织培养物移植到扩散小室中用于骨形态发生蛋白的生物测定。
Clin Orthop Relat Res. 1993 Jan(286):262-70.
7
Induction of smooth muscle cell-like phenotype in marrow-derived cells among regenerating urinary bladder smooth muscle cells.再生膀胱平滑肌细胞中骨髓来源细胞向平滑肌样表型的诱导。
Am J Pathol. 2005 Feb;166(2):565-73. doi: 10.1016/S0002-9440(10)62278-X.
8
Enhancement of human muscle growth in diffusion chambers by bone marrow cells.骨髓细胞在扩散小室中增强人类肌肉生长。
Virchows Arch B Cell Pathol Incl Mol Pathol. 1982;41(1-2):171-80. doi: 10.1007/BF02890279.
9
Myogenesis in adult mammalian skeletal muscle in vitro.成年哺乳动物骨骼肌在体外的肌生成
J Anat. 1981 Jan;132(Pt 1):1-18.
10
Age-related impeded regeneration of mouse minced anterior tibial muscle.与年龄相关的小鼠胫骨前肌切碎后再生受阻
Muscle Nerve. 1982 Feb;5(2):152-61. doi: 10.1002/mus.880050213.
引用本文的文献
1
Induction of bone marrow-derived cells myogenic identity by their interactions with the satellite cell niche.通过骨髓源性细胞与卫星细胞龛的相互作用诱导其成肌特性。
Stem Cell Res Ther. 2018 Sep 27;9(1):258. doi: 10.1186/s13287-018-0993-z.
2
Evaluation of bone marrow mononuclear cells as an adjunct therapy to minced muscle graft for the treatment of volumetric muscle loss injuries.评估骨髓单个核细胞作为切碎肌肉移植辅助疗法治疗大面积肌肉缺损损伤的效果。
Stem Cell Res Ther. 2017 Jun 9;8(1):142. doi: 10.1186/s13287-017-0589-z.
3
Stem cells migration during skeletal muscle regeneration - the role of Sdf-1/Cxcr4 and Sdf-1/Cxcr7 axis.干细胞在骨骼肌再生过程中的迁移——Sdf-1/Cxcr4 和 Sdf-1/Cxcr7 轴的作用。
Cell Adh Migr. 2017 Jul 4;11(4):384-398. doi: 10.1080/19336918.2016.1227911. Epub 2016 Oct 13.
4
Sdf-1 (CXCL12) induces CD9 expression in stem cells engaged in muscle regeneration.基质细胞衍生因子-1（CXCL12）可诱导参与肌肉再生的干细胞中CD9的表达。
Stem Cell Res Ther. 2015 Mar 24;6(1):46. doi: 10.1186/s13287-015-0041-1.
5
Enhancement of muscle regeneration by bone marrow cells in the monkey.骨髓细胞对猴子肌肉再生的促进作用。
Experientia. 1984 May 15;40(5):490-2. doi: 10.1007/BF01952401.
本文引用的文献
1
Promotion of wound repair in mice by application of glucan.应用葡聚糖促进小鼠伤口修复。
J Reticuloendothel Soc. 1980 Jan;27(1):1-11.
2
Skeletal muscle: regeneration and transplantation studies.骨骼肌：再生与移植研究
Br Med Bull. 1980 May;36(2):153-8. doi: 10.1093/oxfordjournals.bmb.a071631.
3
Skeletal muscle regeneration.骨骼肌再生
Muscle Nerve. 1981 May-Jun;4(3):234-45. doi: 10.1002/mus.880040311.
4
Enhancement of human muscle growth in diffusion chambers by bone marrow cells.骨髓细胞在扩散小室中增强人类肌肉生长。
Virchows Arch B Cell Pathol Incl Mol Pathol. 1982;41(1-2):171-80. doi: 10.1007/BF02890279.
5
The regeneration of skeletal muscle. A review.骨骼肌的再生。综述。
Am J Anat. 1973 Jun;137(2):119-49. doi: 10.1002/aja.1001370202.
6
Whole-muscle reimplantation with microneurovascular anastomoses. A functional and histological study.带显微神经血管吻合的全肌再植术。一项功能与组织学研究。
Ann R Coll Surg Engl. 1977 Sep;59(5):393-400.
7
Acceleration of muscle regeneration by bone marrow cells.
Experientia. 1977 Feb 15;33(2):195-7. doi: 10.1007/BF02124062.
8
Regeneration and differentiation of minced anterior tibial muscle explants from mice with MED myopathy.患有肢带型肌营养不良症（MED）的小鼠胫前肌切碎外植体的再生与分化
Lab Invest. 1977 Mar;36(3):303-9.
9
Evidence of fusion between host and donor myoblasts in skeletal muscle grafts.骨骼肌移植中宿主与供体成肌细胞融合的证据。
Nature. 1978 May 25;273(5660):306-8. doi: 10.1038/273306a0.
Zotero 插件