• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Nonsense mutations in the can1 locus of Saccharomyces cerevisiae.酿酒酵母can1基因座中的无义突变。
J Bacteriol. 1983 Jun;154(3):1476-9. doi: 10.1128/jb.154.3.1476-1479.1983.
2
The CAN1 locus of Saccharomyces cerevisiae: fine-structure analysis and forward mutation rates.酿酒酵母的CAN1基因座：精细结构分析和正向突变率
Genetics. 1979 Jan;91(1):35-51. doi: 10.1093/genetics/91.1.35.
3
Effects of spermine on the detection of induced forward mutation at the Can1 locus in yeast: evidence for selection against canavanine-resistant mutants.
Mutat Res. 1979 Nov;63(1):21-34. doi: 10.1016/0027-5107(79)90101-5.
4
Mutators in Saccharomyces cerevisiae: MUT1-1, MUT1-2 and MUT2-1.酿酒酵母中的突变体：MUT1-1、MUT1-2和MUT2-1。
Genetics. 1976 Aug;83(4):655-66. doi: 10.1093/genetics/83.4.655.
5
Recessive UAA suppressors of the yeast Saccharomyces cerevisiae.酿酒酵母的隐性UAA抑制基因
Genetics. 1982 Dec;102(4):653-64. doi: 10.1093/genetics/102.4.653.
6
Allele-specific suppression of temperature-sensitive mutations of the Saccharomyces cerevisiae RAD52 gene.酿酒酵母RAD52基因温度敏感突变的等位基因特异性抑制
Curr Genet. 1996 Feb;29(3):203-10. doi: 10.1007/BF02221549.
7
Patterns of Genetic and Phenotypic Suppression of lys2 Mutations in the Yeast SACCHAROMYCES CEREVISIAE.酵母 SACCHAROMYCES CEREVISIAE 中 lys2 突变的遗传和表型抑制模式。
Genetics. 1979 Sep;93(1):67-79. doi: 10.1093/genetics/93.1.67.
8
Enhanced canavanine uptake is associated with nucleotide permeability in a thymidylate auxotroph of Saccharomyces cerevisiae.在酿酒酵母的胸苷酸营养缺陷型中，刀豆氨酸摄取增强与核苷酸通透性相关。
Curr Genet. 1989 Feb;15(2):129-34. doi: 10.1007/BF00435459.
9
Pathways of ultraviolet mutability in Saccharomyces cerevisiae. III. Genetic analysis and properties of mutants resitant to ultraviolet-induced forward mutation.酿酒酵母中紫外线诱变的途径。III. 对紫外线诱导正向突变具有抗性的突变体的遗传分析及特性
Mutat Res. 1977 May;43(2):179-204. doi: 10.1016/0027-5107(77)90003-3.
10
Frameshift suppression in Saccharomyces cerevisiae. III. Isolation and genetic properties of group III suppressors.酿酒酵母中的移码抑制。III. III类抑制子的分离及遗传特性
Genetics. 1980 Aug;95(4):855-79. doi: 10.1093/genetics/95.4.855.

引用本文的文献

1
Investigating Fission Yeast Mutagenesis Using Canavanine Sensitivity Assays.利用瓜氨酸敏感性检测法研究裂殖酵母的诱变作用。
Methods Mol Biol. 2025;2862:195-208. doi: 10.1007/978-1-0716-4168-2_14.
2
Characterization of the mIF4G Domains in the RNA Surveillance Protein Upf2p.RNA监测蛋白Upf2p中mIF4G结构域的特征分析
Curr Issues Mol Biol. 2023 Dec 29;46(1):244-261. doi: 10.3390/cimb46010017.
3
ER-localized Shr3 is a selective co-translational folding chaperone necessary for amino acid permease biogenesis.内质网定位的 Shr3 是一种选择性共翻译折叠伴侣，对于氨基酸渗透酶的生物发生是必需的。
J Cell Biol. 2023 Sep 4;222(9). doi: 10.1083/jcb.202208060. Epub 2023 Jul 21.
4
The shuttling protein Npl3 promotes translation termination accuracy in Saccharomyces cerevisiae.穿梭蛋白Npl3提高酿酒酵母中的翻译终止准确性。
J Mol Biol. 2009 Dec 4;394(3):410-22. doi: 10.1016/j.jmb.2009.08.067. Epub 2009 Sep 3.
5
The yeast PH domain proteins Slm1 and Slm2 are targets of sphingolipid signaling during the response to heat stress.酵母PH结构域蛋白Slm1和Slm2是热应激反应期间鞘脂信号传导的靶标。
Mol Cell Biol. 2007 Jan;27(2):633-50. doi: 10.1128/MCB.00461-06. Epub 2006 Nov 13.
6
UGA suppressors in Saccharomyces cerevisiae: allelism, action spectra and map positions.酿酒酵母中的UGA抑制基因：等位性、作用光谱和图谱位置。
Genetics. 1988 Jan;118(1):41-7. doi: 10.1093/genetics/118.1.41.

本文引用的文献

1
Patterns of Genetic and Phenotypic Suppression of lys2 Mutations in the Yeast SACCHAROMYCES CEREVISIAE.酵母 SACCHAROMYCES CEREVISIAE 中 lys2 突变的遗传和表型抑制模式。
Genetics. 1979 Sep;93(1):67-79. doi: 10.1093/genetics/93.1.67.
2
Allelic Complementation in the First Gene for Histidine Biosynthesis in SACCHAROMYCES CEREVISIAE. I. Characteristics of Mutants and Genetic Mapping of Alleles.酵母氨酸生物合成的第一个基因中的等位基因互补。I. 突变体的特征和等位基因的遗传图谱。
Genetics. 1973 Jun;74(2):287-305. doi: 10.1093/genetics/74.2.287.
3
Genetic Mapping in Saccharomyces IV. Mapping of Temperature-Sensitive Genes and Use of Disomic Strains in Localizing Genes.酵母的遗传图谱 IV. 温度敏感基因的图谱绘制以及在定位基因中的二倍体菌株的使用。
Genetics. 1973 May;74(1):33-54. doi: 10.1093/genetics/74.1.33.
4
A Critical Evaluation of the Nitrogen Assimilation Tests Commonly Used in the Classification of Yeasts.对酵母分类中常用的氮同化试验的批判性评价。
J Bacteriol. 1946 Sep;52(3):293-301.
5
Serine-inserting UAA suppression mediated by yeast tRNASer.由酵母tRNASer介导的丝氨酸插入UAA抑制作用。
J Mol Biol. 1981 Aug 15;150(3):361-73. doi: 10.1016/0022-2836(81)90552-0.
6
Serine insertion caused by the ribosomal suppressor SUP46 in yeast.酵母中核糖体抑制因子SUP46引起的丝氨酸插入。
J Mol Biol. 1981 Apr 15;147(3):373-9. doi: 10.1016/0022-2836(81)90489-7.
7
Multiplicity of the amino acid permeases in Saccharomyces cerevisiae. I. Evidence for a specific arginine-transporting system.酿酒酵母中氨基酸通透酶的多样性。I. 特定精氨酸转运系统的证据。
Biochim Biophys Acta. 1966 Oct 31;127(2):325-38. doi: 10.1016/0304-4165(66)90387-4.
8
Amino acid replacements resulting from super-suppression of nonsense mutants of iso-1-cytochrome c from yeast.酵母异-1-细胞色素c无义突变体的超抑制所导致的氨基酸替换。
J Mol Biol. 1971 Oct 14;61(1):157-73. doi: 10.1016/0022-2836(71)90213-0.
9
Fine structure of the ura 2 locus in Saccharomyces cervisiae. I. In vivo complementation studies.酿酒酵母ura 2基因座的精细结构。I. 体内互补研究。
Mol Gen Genet. 1971;112(4):354-64. doi: 10.1007/BF00334436.
10
Suppressors in yeast.酵母中的抑制因子。
Curr Top Microbiol Immunol. 1974;64(0):1-47. doi: 10.1007/978-3-642-65848-8_1.

酿酒酵母can1基因座中的无义突变。

Nonsense mutations in the can1 locus of Saccharomyces cerevisiae.

作者信息

Ono B I, Ishino Y, Shinoda S

出版信息

J Bacteriol. 1983 Jun;154(3):1476-9. doi: 10.1128/jb.154.3.1476-1479.1983.

DOI:10.1128/jb.154.3.1476-1479.1983
PMID:6343355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC217629/
Abstract

Yeast mutants resistant to L-canavanine were selected. All were recessive and fell into the can1 complementation group. Nonsense mutations were identified among them by using a set of different suppressors. Frequencies of UAA, UAG, and presumed UGA mutations were 14.8, 0.8, and 0.4%, respectively. A high incidence of nonsense mutations having discriminatory suppression patterns was characteristic of the locus.

摘要

筛选出了对L-刀豆氨酸具有抗性的酵母突变体。所有突变体均为隐性，且都属于can1互补群。通过使用一组不同的抑制子在其中鉴定出了无义突变。UAA、UAG以及推测的UGA突变的频率分别为14.8%、0.8%和0.4%。具有鉴别性抑制模式的无义突变的高发生率是该基因座的特征。