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大鼠急性实验性大肠杆菌附睾炎及其对精子发生的影响。

Acute experimental E. coli epididymitis in the rat and its consequences on spermatogenesis.

作者信息

Lucchetta R, Clavert A, Meyer J M, Bollack C

出版信息

Urol Res. 1983;11(3):117-20. doi: 10.1007/BF00257715.

DOI:10.1007/BF00257715
PMID:6353733
Abstract

The injection of E. Coli into the tail of the epididymis in the rat caused epididymitis. In 20% of the cases, the inflammation is spread through the lymphatic system to the testis. The germinal cells are destroyed in 50% of the cases by the second day, and are not reestablished for several months. Signs of testicular inflammation are not found. The destruction seems to be caused by E. Coli toxins, as shown by injections of killed bacteria.

摘要

将大肠杆菌注射到大鼠附睾尾部会引发附睾炎。在20%的病例中,炎症通过淋巴系统扩散至睾丸。到第二天,50%的病例中生精细胞遭到破坏,且数月内无法恢复。未发现睾丸炎症迹象。如注射死菌所示,这种破坏似乎是由大肠杆菌毒素引起的。

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本文引用的文献

1
Epididymitis: a review of 610 cases.附睾炎:610例病例回顾
J Urol. 1966 Mar;95(3):390-2. doi: 10.1016/S0022-5347(17)63468-2.
2
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Fertil Steril. 1968 Sep-Oct;19(5):748-57. doi: 10.1016/s0015-0282(16)36789-9.
3
On the etiology of epididymitis.论附睾炎的病因
脂多糖和脂磷壁酸在实验性急性附睾炎炎中差异调节附睾细胞因子和趋化因子谱及精子参数。
Sci Rep. 2018 Jan 8;8(1):103. doi: 10.1038/s41598-017-17944-4.
4
Epididymitis: revelations at the convergence of clinical and basic sciences.附睾炎:临床与基础科学交叉领域的新发现
Asian J Androl. 2015 Sep-Oct;17(5):756-63. doi: 10.4103/1008-682X.155770.
5
Immunophysiology and pathology of inflammation in the testis and epididymis.睾丸和附睾炎症的免疫生理学与病理学
J Androl. 2011 Nov-Dec;32(6):625-40. doi: 10.2164/jandrol.111.012989. Epub 2011 Jul 15.
6
Toll-like receptors and signalling in spermatogenesis and testicular responses to inflammation--a perspective. Toll 样受体及其信号在精子发生和睾丸对炎症反应中的作用——一种观点。
J Reprod Immunol. 2011 Mar;88(2):130-41. doi: 10.1016/j.jri.2011.01.010. Epub 2011 Feb 18.
7
Acute vesiculitis and its prostatic complications caused by E. coli in the rat.
Urol Res. 1986;14(5):265-6. doi: 10.1007/BF00256571.
8
Acute experimental unilateral orchitis in the rabbit and its effect on fertility.家兔急性实验性单侧睾丸炎及其对生育能力的影响。
Int Urol Nephrol. 1992;24(3):291-7. doi: 10.1007/BF02549538.
J Urol. 1971 Apr;105(4):531-3. doi: 10.1016/s0022-5347(17)61567-2.
4
Semen analysis in unilateral epididymitis.单侧附睾炎的精液分析
N Y State J Med. 1968 Nov 1;68(21):2769-70.
5
Etiology, manifestations and therapy of acute epididymitis: prospective study of 50 cases.急性附睾炎的病因、表现及治疗:50例前瞻性研究
J Urol. 1979 Jun;121(6):750-4. doi: 10.1016/s0022-5347(17)56978-5.