MM 14201，一种由链霉菌属的一个物种产生的具有抗菌活性的新型环氧醌衍生物。
MM 14201, a new epoxyquinone derivative with antibacterial activity produced by a species of Streptomyces.
作者信息
Box S J, Gilpin M L, Gwynn M, Hanscomb G, Spear S R, Brown A G
出版信息
J Antibiot (Tokyo). 1983 Dec;36(12):1631-7. doi: 10.7164/antibiotics.36.1631.
PMID:6363372
Abstract
A new antibiotic designated MM 14201 has been detected in a culture of Streptomyces sp. NCIB 11813. Methods for the production and purification of MM 14201 are described. Biological evaluation has shown it has broad spectrum antibacterial activity being most effective against Serratia and Pseudomonas sp. Structural studies are reported which have demonstrated MM 14201 is a new epoxyquinone derivative.
摘要
在链霉菌属菌株NCIB 11813的培养物中检测到一种名为MM 14201的新型抗生素。本文描述了MM 14201的生产和纯化方法。生物学评估表明，它具有广谱抗菌活性，对沙雷氏菌属和假单胞菌属最为有效。本文还报道了结构研究，结果表明MM 14201是一种新型环氧醌衍生物。
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