Rowe I F, Worsley A M, Donnelly P, Catovsky D, Goldman J M, Galton D, Pepys M B
J Clin Pathol. 1984 Mar;37(3):263-6. doi: 10.1136/jcp.37.3.263.
C reactive protein concentration was measured serially in 19 patients with leukaemia after bone marrow transplantation. Six episodes of graft versus host disease occurred in the presence of fever but with no evidence of infection, and these were associated with C reactive protein concentrations as high as 200 mg/l. C reactive protein values were also increased in 12 febrile episodes associated with infection, in seven of which graft versus host disease was also present. C reactive protein concentrations are of no value in differentiating infection from graft versus host disease, but in both cases they may be useful as an objective index of response to appropriate treatment.
对19例骨髓移植后的白血病患者连续测定C反应蛋白浓度。6例发生移植物抗宿主病的患者伴有发热，但无感染证据，这些患者的C反应蛋白浓度高达200mg/L。在12例与感染相关的发热发作中，C反应蛋白值也升高，其中7例同时存在移植物抗宿主病。C反应蛋白浓度在区分感染和移植物抗宿主病方面没有价值，但在这两种情况下，它们都可能作为对适当治疗反应的客观指标。
