在一项双盲研究中，葡萄糖酸锌含片可缩短普通感冒的病程。
Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study.
作者信息
Eby G A, Davis D R, Halcomb W W
出版信息
Antimicrob Agents Chemother. 1984 Jan;25(1):20-4. doi: 10.1128/AAC.25.1.20.
Abstract
As a possible treatment for common colds, we tested zinc gluconate lozenges in a double-blind, placebo-controlled, clinical trial. One 23-mg zinc lozenge or matched placebo was dissolved in the mouth every 2 wakeful h after an initial double dose. After 7 days, 86% of 37 zinc-treated subjects were asymptomatic, compared with only 46% of 28 placebo-treated subjects (P = 0.0005). Side effects or complaints were usually minor and consisted mainly of objectionable taste and mouth irritation. Zinc lozenges shortened the average duration of common colds by about 7 days.
摘要
作为普通感冒的一种可能治疗方法，我们在一项双盲、安慰剂对照的临床试验中对葡萄糖酸锌含片进行了测试。在初始双倍剂量后，每清醒2小时在口中溶解一片23毫克的锌含片或匹配的安慰剂。7天后，37名接受锌治疗的受试者中有86%无症状，而28名接受安慰剂治疗的受试者中只有46%无症状（P = 0.0005）。副作用或不适通常较轻，主要包括味道不佳和口腔刺激。锌含片使普通感冒的平均持续时间缩短了约7天。
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