胶质纤维酸性蛋白定位于晶状体上皮。
Glial fibrillary acidic protein is localized in the lens epithelium.
作者信息
Hatfield J S, Skoff R P, Maisel H, Eng L
出版信息
J Cell Biol. 1984 May;98(5):1895-8. doi: 10.1083/jcb.98.5.1895.
Abstract
The epithelium of the mouse lens stains intensely with antisera to glial fibrillary acidic protein (GFAP). A protein co-migrating with GFAP and immunoreactive with antisera to GFAP can be demonstrated in lens epithelium protein extracts by immunoblots. GFAP has previously been considered unique to cells of neural origin, but this study demonstrates that ectodermally derived cells express GFAP or a highly similar protein.
摘要
小鼠晶状体的上皮细胞与抗胶质纤维酸性蛋白（GFAP）的抗血清发生强烈染色反应。通过免疫印迹法可在晶状体上皮蛋白提取物中证实一种与GFAP共迁移且与抗GFAP抗血清发生免疫反应的蛋白质。GFAP此前一直被认为是神经源性细胞所特有的，但这项研究表明，外胚层来源的细胞表达GFAP或一种高度相似的蛋白质。
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