Tiemens K M, Shipley P L, Correia R A, Shields D S, Guerrant R L
Antimicrob Agents Chemother. 1984 May;25(5):653-4. doi: 10.1128/AAC.25.5.653.
In contrast to prior experience in northeastern Brazil, three of four Shigella flexneri strains recently isolated from patients with acute inflammatory diarrhea in this setting were found to be resistant to sulfamethoxazole-trimethoprim. The resistant strains contained large, different plasmids, two of which were transferred with sulfamethoxazole-trimethoprim resistance to Escherichia coli K-12 recipient strains.
与巴西东北部之前的经验相反,最近在此环境中从急性炎症性腹泻患者分离出的4株弗氏志贺氏菌中,有3株对复方新诺明耐药。耐药菌株含有大型、不同的质粒,其中两个质粒携带对复方新诺明的耐药性转移至大肠杆菌K-12受体菌株。