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本文引用的文献

1
Prospective, randomized comparative study of clindamycin, chloramphenicol, and ticarcillin, each in combination with gentamicin, in therapy for intraabdominal and female genital tract sepsis.克林霉素、氯霉素及替卡西林分别与庆大霉素联合用于治疗腹腔内感染和女性生殖道败血症的前瞻性随机对照研究。
J Infect Dis. 1980 Sep;142(3):384-93. doi: 10.1093/infdis/142.3.384.
2
Intravenous metronidazole for treatment of infections involving anaerobic bacteria.静脉注射甲硝唑用于治疗涉及厌氧菌的感染。
Antimicrob Agents Chemother. 1982 Mar;21(3):441-9. doi: 10.1128/AAC.21.3.441.
3
A randomized comparison of cefoxitin with or without amikacin and clindamycin plus amikacin in surgical sepsis.头孢西丁联合或不联合阿米卡星与克林霉素加阿米卡星治疗外科脓毒症的随机对照研究
Ann Surg. 1981 Mar;193(3):318-23. doi: 10.1097/00000658-198103000-00011.
4
Impact of cefoperazone therapy on fecal flora.头孢哌酮治疗对粪便菌群的影响。
Antimicrob Agents Chemother. 1982 Aug;22(2):226-30. doi: 10.1128/AAC.22.2.226.
5
Antibacterial activity and beta-lactamase stability of ceftazidime, an aminothiazolyl cephalosporin potentially active against Pseudomonas aeruginosa.头孢他啶的抗菌活性及β-内酰胺酶稳定性，一种对铜绿假单胞菌可能具有活性的氨噻唑基头孢菌素。
Antimicrob Agents Chemother. 1982 Jan;21(1):11-8. doi: 10.1128/AAC.21.1.11.
6
Ceftazidime--a new extended-spectrum cephalosporin.头孢他啶——一种新型广谱头孢菌素。
Lancet. 1982 May 22;1(8282):1152-6. doi: 10.1016/s0140-6736(82)92228-0.
7
Susceptibility of anaerobic bacteria to 23 antimicrobial agents.厌氧菌对23种抗菌剂的敏感性。
Antimicrob Agents Chemother. 1976 Oct;10(4):736-52. doi: 10.1128/AAC.10.4.736.

克林霉素与头孢他啶联合应用的体外抗菌活性。

In vitro antibacterial activity of the combination of clindamycin and ceftazidime.

作者信息

George W L

出版信息

Antimicrob Agents Chemother. 1984 May;25(5):657-8. doi: 10.1128/AAC.25.5.657.

DOI:10.1128/AAC.25.5.657
PMID:6375564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC185610/
Abstract

A total of 49 anaerobic and 52 aerobic or facultative bacteria were tested for their susceptibilities to clindamycin and ceftazidime alone and in combination. Synergy was noted for 11 strains, whereas antagonism was not detected. The combination of clindamycin and ceftazidime may prove to be useful for the treatment of severe mixed infections caused by anaerobes and aerobes or facultative bacteria.

摘要

共对49株厌氧菌和52株需氧菌或兼性菌进行了单独及联合使用克林霉素和头孢他啶的药敏试验。观察到11株菌有协同作用，未检测到拮抗作用。克林霉素和头孢他啶联合使用可能对治疗由厌氧菌与需氧菌或兼性菌引起的严重混合感染有效。