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相似文献

1
Kinetics of methylation in Escherichia coli K-12.大肠杆菌K-12中甲基化的动力学
J Bacteriol. 1984 Jul;159(1):421-3. doi: 10.1128/jb.159.1.421-423.1984.
2
Absence in Bacillus subtilis and Staphylococcus aureus of the sequence-specific deoxyribonucleic acid methylation that is conferred in Escherichia coli K-12 by the dam and dcm enzymes.枯草芽孢杆菌和金黄色葡萄球菌中不存在由dam和dcm酶在大肠杆菌K-12中赋予的序列特异性脱氧核糖核酸甲基化。
J Bacteriol. 1981 Jul;147(1):259-61. doi: 10.1128/jb.147.1.259-261.1981.
3
The rate of Dam-mediated DNA adenine methylation in Escherichia coli.
Gene. 1988 Dec 25;74(1):189-90. doi: 10.1016/0378-1119(88)90283-1.
4
[DNA methylation in the cells of Escherichia coli MRE 600 in the presence of S-methylmethionine].
Biokhimiia. 1981 Dec;46(12):2160-3.
5
Methylation of newly synthesized ribosomal protein L11 in a DNA-directed in vitro system.在一个DNA指导的体外系统中新合成的核糖体蛋白L11的甲基化作用。
J Biol Chem. 1980 Sep 25;255(18):8706-10.
6
RNA polymerase. Direct evidence for a unique topographical site for initiation.
J Biol Chem. 1985 Dec 25;260(30):16310-5.
7
Adenine methylation of Okazaki fragments in Escherichia coli.大肠杆菌中冈崎片段的腺嘌呤甲基化
J Bacteriol. 1976 Dec;128(3):853-4. doi: 10.1128/jb.128.3.853-854.1976.
8
The oriC unwinding by dam methylation in Escherichia coli.大肠杆菌中dam甲基化介导的oriC解旋。
Nucleic Acids Res. 1988 Jun 10;16(11):5067-73. doi: 10.1093/nar/16.11.5067.
9
Effect of 5-azacytidine on deoxyribonucleic acid methylation in Escherichia coli K12.5-氮杂胞苷对大肠杆菌K12中脱氧核糖核酸甲基化的影响。
Biochem Pharmacol. 1984 Aug 15;33(16):2675-9. doi: 10.1016/0006-2952(84)90644-0.
10
Isolation and in vitro restriction of unmethylated DNA from Escherichia coli K.
Biochim Biophys Acta. 1974 Oct 11;366(2):135-42. doi: 10.1016/0005-2787(74)90327-x.

引用本文的文献

1
Modern aspects of the structural and functional organization of the DNA mismatch repair system.DNA 错配修复系统的结构和功能组织的现代方面。
Acta Naturae. 2013 Jul;5(3):17-34.
2
The role of the preserved sequences of Dam methylase.Dam甲基化酶保守序列的作用。
Nucleic Acids Res. 1993 Jul 11;21(14):3183-90. doi: 10.1093/nar/21.14.3183.
3
Cytosine methylation inhibits replication of African cassava mosaic virus by two distinct mechanisms.
Nucleic Acids Res. 1993 Jul 25;21(15):3445-50. doi: 10.1093/nar/21.15.3445.
4
Biological role of DNA methylation: sequence-specific single-strand breaks associated with hypomethylation of GATC sites in Escherichia coli DNA.DNA甲基化的生物学作用：与大肠杆菌DNA中GATC位点低甲基化相关的序列特异性单链断裂
J Bacteriol. 1986 Dec;168(3):1487-90. doi: 10.1128/jb.168.3.1487-1490.1986.
5
Interaction of an antimutator gene with DNA repair pathways in Escherichia coli K-12.
Mol Gen Genet. 1985;198(2):336-47. doi: 10.1007/BF00383016.
6
Strand targeting signal(s) for in vivo mutation avoidance by post-replication mismatch repair in Escherichia coli.大肠杆菌中通过复制后错配修复避免体内突变的链靶向信号。
Mol Gen Genet. 1988 Nov;214(3):574-8. doi: 10.1007/BF00330497.
7
The B- to Z-DNA equilibrium in vivo is perturbed by biological processes.体内B型到Z型DNA的平衡会受到生物过程的干扰。
Proc Natl Acad Sci U S A. 1988 Oct;85(19):7069-73. doi: 10.1073/pnas.85.19.7069.
8
Overproduction of DnaA protein stimulates initiation of chromosome and minichromosome replication in Escherichia coli.DnaA蛋白的过量产生会刺激大肠杆菌中染色体和微型染色体复制的起始。
Mol Gen Genet. 1987 Jan;206(1):51-9. doi: 10.1007/BF00326535.
9
GATC sequence and mismatch repair in Escherichia coli.大肠杆菌中的GATC序列与错配修复
EMBO J. 1986 Aug;5(8):2009-13. doi: 10.1002/j.1460-2075.1986.tb04457.x.
10
Evidence that adenine methylation influences DNA-protein interactions in Escherichia coli.腺嘌呤甲基化影响大肠杆菌中DNA-蛋白质相互作用的证据。
J Bacteriol. 1985 Oct;164(1):490-3. doi: 10.1128/jb.164.1.490-493.1985.

本文引用的文献

1
Escherichia coli K-12 clones that overproduce dam methylase are hypermutable.过量产生dam甲基化酶的大肠杆菌K-12克隆具有高度可突变性。
J Bacteriol. 1981 Jan;145(1):644-6. doi: 10.1128/jb.145.1.644-646.1981.
2
Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.缺乏甲基化指导的DNA错配修复的大肠杆菌突变体
Proc Natl Acad Sci U S A. 1980 Feb;77(2):1063-7. doi: 10.1073/pnas.77.2.1063.
3
Studies on the biological role of DNA methylation: V. The pattern of E.coli DNA methylation.DNA甲基化的生物学作用研究：V. 大肠杆菌DNA甲基化模式
Nucleic Acids Res. 1982 Nov 25;10(22):7247-59. doi: 10.1093/nar/10.22.7247.
4
Effects of high levels of DNA adenine methylation on methyl-directed mismatch repair in Escherichia coli.高水平DNA腺嘌呤甲基化对大肠杆菌中甲基导向错配修复的影响。
Genetics. 1983 Aug;104(4):571-82. doi: 10.1093/genetics/104.4.571.
5
Map positions and specificities of suppressor mutations in Escherichia coli K-12.大肠杆菌K-12中抑制突变的图谱位置和特异性
Genetics. 1965 Aug;52(2):319-40. doi: 10.1093/genetics/52.2.319.
6
Culture medium for enterobacteria.用于肠道细菌的培养基。
J Bacteriol. 1974 Sep;119(3):736-47. doi: 10.1128/jb.119.3.736-747.1974.
7
Isolation of deoxyribonucleic acid methylase mutants of Escherichia coli K-12.大肠杆菌K-12脱氧核糖核酸甲基化酶突变体的分离
J Bacteriol. 1973 Jun;114(3):1143-50. doi: 10.1128/jb.114.3.1143-1150.1973.
8
Escherichia coli mutants uvr D and uvr E deficient in gene conversion of lambda-heteroduplexes.缺乏λ异源双链体基因转换功能的大肠杆菌uvr D和uvr E突变体。
Mol Gen Genet. 1975 Aug 27;139(3):233-43. doi: 10.1007/BF00268974.
9
Repair tracts in mismatched DNA heteroduplexes.修复错配DNA异源双链体中的修复片段。
Proc Natl Acad Sci U S A. 1976 Nov;73(11):4135-9. doi: 10.1073/pnas.73.11.4135.
10
Two sequence-specific endonucleases from Moraxella bovis.来自牛莫拉菌的两种序列特异性核酸内切酶。
J Mol Biol. 1977 Jul;114(1):169-79. doi: 10.1016/0022-2836(77)90290-x.

大肠杆菌K-12中甲基化的动力学

Kinetics of methylation in Escherichia coli K-12.

作者信息

Lyons S M, Schendel P F

出版信息

J Bacteriol. 1984 Jul;159(1):421-3. doi: 10.1128/jb.159.1.421-423.1984.

DOI:10.1128/jb.159.1.421-423.1984
PMID:6376478
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC215653/
Abstract

Newly synthesized DNA is undermethylated in E. coli K-12. The amount of N6-methyl deoxyadenylic acid in labeled DNA varied from 0.3 mol% of total adenine for a 2-min pulse to 1.7 mol% for DNA that was labeled for more than two generations.

摘要

新合成的DNA在大肠杆菌K-12中处于低甲基化状态。标记DNA中N6-甲基脱氧腺苷酸的含量，对于2分钟脉冲标记的DNA，占腺嘌呤总量的0.3摩尔%；对于标记超过两代的DNA，则为1.7摩尔%。