Woodruff A W, Bowen E T, Platt G S
Br Med J. 1978 Apr 15;1(6118):956-8. doi: 10.1136/bmj.1.6118.956.
Examination of sera from 86 travellers to Britain from tropical Africa disclosed evidence of past infection with 10 identifiable viruses, of which the most important were O'nyong-nyong, dengue, chikungunya, and Ntaya. The findings indicate that infection with O'nyong-nyong may be acquired sporadically in Nigeria, Ghana, and Sierra Leone, where it has not previously been identified. Chikungunya infection had not been recorded in West Africa other than Nigeria and Senegal. Patients from Sierra Leone and contiguous Liberia had antibodies to this infection. An outbread of dengue fever in the Seychelles in early 1977 was confirmed. Ntaya virus, though known in Uganda, Cameroon, and Zaire, appears also to be transmitted in Kenya, Nigeria, and Zambia. Clinical studies indicated that chikungunya infection may present with alimentary features, possibly with jaundice. The clinical features of Ntaya infection may include kizarre neurological manifestations in addition to fever. The absence of Lassa antibodies among these travellers suggested that this infection is not a common hazard among such persons.
对86名从热带非洲前往英国的旅行者的血清进行检测后发现，他们曾感染过10种可识别的病毒，其中最重要的是奥尼永-尼永病毒、登革热病毒、基孔肯雅病毒和恩塔亚病毒。研究结果表明，在尼日利亚、加纳和塞拉利昂可能会散发性感染奥尼永-尼永病毒，此前在这些地方尚未发现过该病毒。除尼日利亚和塞内加尔外，西非其他地区均未记录到基孔肯雅病毒感染情况。来自塞拉利昂及相邻的利比里亚的患者体内有针对该病毒感染的抗体。1977年初塞舌尔群岛登革热疫情得到确认。恩塔亚病毒虽在乌干达、喀麦隆和扎伊尔被发现，但在肯尼亚、尼日利亚和赞比亚似乎也有传播。临床研究表明，基孔肯雅病毒感染可能伴有消化道症状，可能还会出现黄疸。恩塔亚病毒感染的临床特征除发热外，可能还包括怪异的神经症状。这些旅行者中未检测到拉沙热抗体，这表明此类人群感染拉沙热并非常见风险。
