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新明托病毒:一种来自阿拉斯加蜱虫的新型弹状病毒。

New Minto virus: a new rhabdovirus from ticks in Alaska.

作者信息

Ritter D G, Calisher C H, Muth D J, Shope R E, Murphy F A, Whitfield S G

出版信息

Can J Microbiol. 1978 Apr;24(4):422-6. doi: 10.1139/m78-069.

Abstract

Three strains of a virus were isolated from Haemaphysalis leporis-palustris (Packard) ticks removed from snowshoe hares (Lepus americanus Erxleben) in east central Alaska. We suggest that the virus be named New Minto for the location in which the ticks were collected. Prototype New Minto virus is sensitive to the action of sodium deoxycholate and kills suckling mice by the intracerebral but not intraperitoneal route; weaned mice do not die after intracerebral, intraperitoneal, or subcutaneous inoculation. The virus produces plaque in serially propagated Vero but not in primary Pekin duck embryo cells. By complement-fixation and neutralization tests New Minto is related to Sawgrass Virus, a hitherto ungrouped virus from Florida. The establishment of a Sawgrass group is suggested. In addition, Sawgrass virus was found by electron microscopy to belong to the Family Rhabdoviridae.

摘要

从阿拉斯加中东部的白靴兔(Lepus americanus Erxleben)身上采集的沼泽兔血蜱(Haemaphysalis leporis-palustris (Packard))中分离出了三株病毒。我们建议将该病毒命名为新明托病毒,以纪念采集蜱虫的地点。新明托病毒原型对脱氧胆酸钠敏感,通过脑内接种而非腹腔接种可致乳鼠死亡;断奶小鼠经脑内、腹腔或皮下接种后不会死亡。该病毒在连续传代的非洲绿猴肾细胞(Vero)中可产生蚀斑,但在原代北京鸭胚细胞中则不能。通过补体结合试验和中和试验发现,新明托病毒与锯齿草病毒有关,锯齿草病毒是一种来自佛罗里达州的尚未归类的病毒。建议设立一个锯齿草病毒组。此外,通过电子显微镜观察发现锯齿草病毒属于弹状病毒科。

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